| This research project is divided into syndrome and clinical parts:1.The research on syndrome:Objective:In this study,164 cases are observed in patients with syndrome, to investigate the clinical characteristics of depression, tcm pathogenesis and the most common symptoms.Methods:(1) Summarizing the constituent ratio of depression gender, age, character etc. (2) Application of depression checklist (SDS) analyzing depression mild, heavy distribution. Application of Hamilton Depression Scale (HAMD), Pittsburgh Sleep Quality Index Scale (PSQI), anxiety checklist (SAS) analyzing accompanied sleep obstacles Anxiety. (3) Development of clinical symptoms observed table, each symptom score to quantify all the general symptoms assessed with 0,1,2,3,4 points,but tongue and pulse picture do not participate, in order to sum up the major depression symptoms and pathogenesis.Results:(1)164 cases are from 18 to 74 years old, mean age is 35.22±12.30. In the general information, women for 57.3%.Education for secondary schools and universities for 75%. Manual workers for 47.6%. 83.6% married. Impetuous for 30.6%. Income less than 3,000 yuan per month for 72.5%.(2) Difficulty falling asleep, sleep lightly and waking early for 57.9% of all. Mental anxiety for 72.1%.Mild and moderate depression for 90.9%.(3) Six types of syndrome:Gan huo rao xin,gan qi yu zhi,tan qi yu jie, xin pi liang xu, gan shen yin xu, yin xu huo wang, and gan huo rao xin type of which accounted for 32.9%. A total of 21 main symptoms,and the main are the spirit ones.Conclusion:In the 164 cases of the observation, to the majority of young people, including women, education secondary schools and universities, laborers, married, impetuous character, income less than 3,000 yuan per month.Sleep difficulties, sleep lightly, early awakening all the three majority.Mostly mental anxiety. Mild and moderate depression in the majority. TCM to the majority of psychiatric symptoms, gan huo rao xin type being the most common disturbance of evidence.2.The research of clinical effect:Objective:To explore the effect of Jieyu Qingxin Anshen tang and Xiaoyaosan intervening the depression of gan huo rao xin type.Methods:54 cases of the depressive patients who meet the inclusion criteria are for the comparative study on Jieyu Qinxin Anshen tang and Xiaoyaosan. Both groups are treated for 12 weeks and are follow-up after six months. Assessing score with "syndromes of depression clinical observation table", SDS, SAS, PSQI.Results:The comparison of the total effective rate and scale score results (1)The syndromes and the scale score total efficiency at each time point treatment:①The syndrome total effective rate, P<0.05.②The syndrome scale score at each time point comparison:Group comparison:The treatment and control groups at the treatment of 4weeks,8weeks,12weeks,six months follow-up, P<0.05. Between groups:Depression, pessimism, in comparing the two groups treated for 4 weeks, p>0.05. Treated for 8 weeks, 12 weeks, six months follow-up, p<0.05. Interested in dry, meditation not gathering treated for 4 weeks,8 weeks,12 weeks, six months follow-up, p<0.05. Less sleep soundly, irritability treated for 4 weeks,8 weeks,12 weeks, six months follow-up, p>0.05.Xiongxie fullness six months follow-up, p<0.05. (2) The SDS scale efficiency and the total scale score at each time point comparison①The SDS scale the total effective rate, P<0.05.②The SDS scale score comparison:Group comparison, P<0.01, between the two groups, P<0.01.(3)The comparison of SAS scale efficiency and the total scale score at each time point①The SAS scale the total effective rate, P<0.05.②The SAS scale score comparison: Group comparison, P<0.01, between groups, P<0.05.(4) The comparison of PSQI scale efficiency and the total scale score at each time point①The PSQI total effective scale, P<0.05, significantly.②The PSQI scale score comparison:Group comparison, P<0.01.Between groups, P<0.01.Conclusions:The findings about Jie Yu Qingxin Anshen Tang is effective and the treatment of depression is safe.
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