Clinical Effect Observation Of Chaiqin Ningshen Decoction In Treating Chronic Insomnia(Ganyu Huahuo)

Objective: Through clinical observation to preliminarily evaluate the clinical efficacy and security of chaiqin ningshen decoction in treating chronic insomnia(ganyu huahuo),describe the mechanism of chaiqin ningshen decoction in the treatment of chronic insomnia,and explore a better traditional chinese medicine treatment method for treating chronic insomnia(ganyu huahuo).Methods: This study had selected 72 patients with chronic insomnia(ganyu huahuo)who met the inclusion criteria.Divided patients into control group and treatment group with each group of 36 people by using simple random.Both groups received basic treatment,the treatment group oral chaiqin ningshen decoction and the control group oral shumian capsule.After 4 weeks of clinical trial research and 3 months of follow-up,Pittsburgh sleep quality index and TCM syndrome score of the patients at 4 weeks and 3 months were recorded as efficacy evaluation indexes.Statistical analysis of data using medical statistics,to study the clinical effect of chaiqin ningshen decoction on chronic insomnia(ganyu huahuo).Results: During the treatment and follow-up,72 patients enrolled in the study were not detached.Compared the basic data of gender,age,PSQI score and TCM syndrome score before the treatment,suggesting that the two groups of patients were comparable(P >0.05).(1)The treatment group total effectiveness was 94.44% after the treatment,and there was 86.11% in the control group.The difference was significant(P < 0.05).After 3 months of follow-up,the treatment group total effectiveness was 88.89%,and there was 86.11% in the control group.The difference was significant(P < 0.05).This indicated that the treatment group chaiqin ningshen decoction was better than the control group shumian capsule in terms of therapeutic effect.(2)After treatment,the treatment group and the control group were compared with those before treatment respectively,the PSQI score and TCM syndrome score werechanged.P < 0.05 indicated that the difference was statistically significant.It is pointed out that drugs in the treatment group and the control group both can improve the TCM syndromes and patients' sleep quality.After treatment,the PSQI score and TCM syndrome score of the two groups were compared by statistical software,suggesting differences(P <0.05),indicating that the effect of chaiqin ningshen decoction was better than shumian capsule.(3)Compared the PSQI score and TCM syndrome score of the treatment group and the control group after 3 months of follow-up,P < 0.05 indicated that the difference was statistically significant and showed that the therapeutic effect of chaiqin ningshen decoction in the treatment group was better than that of shumian capsule in the control group.The PSQI score and TCM syndrome score in the treatment group after follow-up were compared with those after treatment,there was no significant difference(P > 0.05).The Pittsburgh sleep quality index and TCM syndrome score in the control group after follow-up were compared with those after treatment,suggesting differences(P < 0.05),it indicated that the curative effect of chaiqinningshen decoction was more stable and better than shumian capsule after 3 months.(4)Safety evaluation: no adverse reactions occurred in 72 patients during the clinical study and follow-up.Conclusion: According to clinical observation,chaiqin ningshen decoction has definite clinical effect in treating chronic insomnia(ganyu huahuo),which can improve the clinical symptoms and sleep quality of patients.The therapeutic effect of Chaiqin Ningshen Decoction is better than Shumian Capsule,which is worthy of further promotion and research.