The Clinical Study Of The Qingfeihuatan Granule In Treating Post-Infectious Cough And The Impact On Serum IL-8

Objective:To observe the Qingfei Huatan Granule in the treatment of post-infectious cough (Phleg-heat by stagnating lung) in patients with clinical symptoms and signs of improvement and the impact on serum IL-8, an objective evaluation of its clinical efficacy.Methods:Selected post-infectious cough (Phleg-heat by stagnating lung) 62 cases of patients, the use of randomized, single-blind control method, divided into experimental group 31 cases and control group 31 cases. Treatment group were given oral granule Qingfei Huatan heat treatment, the control group were given Keke capsule in the treatment of cough. Before and after treatment were observed in patients with symptoms and signs of improvement and serum IL-8 levels.Results:1.Qingfei Huatan Granule in the treatment of post-infectious cough significant clinical efficacy is significant, of which the total effective rate was 93.55%, control rate was 61.29 %.2.Qingfei Huatan Granule of post-infectious cough rough cough, expectoration, sputum color quality sputum, cough speak in a gruff voice, dry mouth, constipation,significantly improve, especially for cough to improve the situation is better than the control group (P<0.05). Onset time was for the 2.90±0.944days, Remission time was for the 4.68±0.820 days.3.Qingfei Huatan Granule can reduce post-infectious cough in patients with IL-8 levels significantly lower than before treatment, the difference was significant (P<0.05).Conclusion:1.Qingfei Huatan Granule can be effective in improving post-infectious cough in patients with symptoms and signs.2.Qingfei Huatan Granule can reduce post-infectious cough in patients with IL-8 levels.3.Qingfei Huatan Granule has a significant clinical efficacy with no adverse reactions.