| Objective: Measurement of depression in rat blood, Triiodothyronine,Thyroxine and Thyrotropin changes of the spleen to the GuiPiSoup in the treatment of depression in rats.Methods: The experimental method used to copy chronic stress rat model of depression. Experimental animals were divided into regular group, model group, optimal solution group and GuiPiSoup high, medium and low dose group. Observation of body weight in rats, and open boxes in accordance with experiments conducted on rats behavior detection. The first 42 days in the experimental rats were sacrificed, femoral artery blood, separation of plasma, serum, measured by radioimmunoassay using rat plasma T3,T4andTSH levels.Results: Compared with the regular group, model group, the slower pace of growth of rat body weight, the scores of horizontal movement and vertical movement reduced, blood T4 levels reduced,T3 and TSH levels have remarkable differences. GuiPiSoup in each group and the group optimal solution to increase the growth rate of body weight and movement of Behavior Science scores, and can add the blood T4 levels.Conclusion: GuiPiSoup can add the blood T4 levels on chronic stress-induced irritation in rats the role of an antidepressant, which may be corrected through the HPT-axis to achieve. |