Clinical Research On Effect Of Micro-invasive Puncture Surgery On The Levels Of D-dimer In Plasm And Traditional Chinese Medicine's Syndrome Of Patients With Hypertensive Intracerebral Hemorrhage

Objective:(1)Observation of micro-invasive puncture surgery of hypertensive intracerebral hemorrhage in patients with plasma D-dimer and clinical neurological deficit scores of the impact indicators to explore the relationship between the two areas.(2)Discussion micro-invasive puncture surgery on patients with hypertensive cerebral hemorrhage before and after treatment the effects of Chinese medicine's syndrome.(3)Discussion the correlation of Chinese medicine's syndrome and plasma D-dimer in hypertensive intracerebral hemorrhage patients.Methods:Guided by the principle of informed consent,the patients who would be consistent with the inclusion criteria were divided into micro-invasive puncture surgery group(32 cases)and conventional medical treatment group(28 cases) in accordance with the wishes of the families of patients.All cases were treated immediately in the hospital.The levels of D-dimer were measured on being in hospital,3th d,7th d,14th d and 30th d.In the same time, the neural function deficiency scores were recorded,and the Chinese medicine's syndrome type of 60 patients was differentiated.Results:The levels of D-dimer in plasm raise before 24 h onset of HICH,increase more obvious on 3th day,rise to the highest on 7th day,decreased on 14th day,reduce down to around normal levels.After treatment,the levels of D-dimer in plasm were lower significantly in micro-invasive puncture surgery group than in conventional medical treatment group,while the neural function deficiency score was significantly lower in the micro-invasive puncture surgery group than that in the conventional medical treatment group.Statistically significant difference between the two groups,and with time differences more obvious.Before treatment of micro-invasive puncture surgery,syndrome types of TanShiMengShe,FengHuoShangRao, FengTanHuoKang,and FengTanYuZu were the commonest,while QiXuXueYu,YinXuFengDong and TanReFuShi were the most commonly syndrome types after treatment.Compari- son of the syndrome types between before and after the micro-invasive puncture surgery within 1 month showed that the syndromes of deficiency did not change,while syndromes of TanShiMengShen,FengHuoShangRao,FengTanHuoKang remarkably have changed;In the different syndrome types of HICH,the level of D-dimer of ones is obviously distinguishing than others,excepting TanShiMengShen,FengTanHuoKang and the level of D-dimer in FengHuoShangRao,TanShiMengShen,FengTanHuoKang and TanReFuShi is obviously higer.Conclusion:Micro-invasive puncture surgery could significantly reduce the neural function deficiency scores and the level of D-dimer of patients with HICH.Micro-invasive puncture surgery treatment are superior to conventional medical treatment in post-injury protection and improvement of nerve function defects after cerebral hemorrhage.The level of D-dimer in plasma is related to curative effect of micro-invasive puncture surgery in HICH.Although micro-invasive puncture surgery treatment could relieve patients' symptoms of excess in superficiality,it can't radically change the pathogenetic nature of HICH,namely,the deficiency in origin and excess in superficiality,which indicates that one should pay full attention to the importance and necessity of HICH after micro-invasive puncture surgery;The nervous impairment of HICH could be diguosed according to Chinese medicine's syndrome type,The levels of D-dimer is related to Chinese medicine's syndrome-type identification.The whole research is going to richen and complete the theory of TCM(traditional Chinese medicine).