Analysis Of Relevant Factors Affecting The Prognosis Of Minimally Invasive Puncture Hematoma Removal For Hypertensive Intracerebral Hemorrhage

Objective:To analyze the prognostic factors affecting minimally invasive puncture hematoma removal for hypertensive intracerebral hemorrhage(hypertensive intracerebral hemorrhage,HICH)and explore its prognostic predictors in order to improve the therapeutic effect.Methods:Retrospective analysis of clinical data of 129 patients with hypertensive intracerebral hemorrhage treated with minimally invasive hematoma removal in the first affiliated hospital of Suzhou University from February 2013 to August 2019,including the patient’s sex,age,preoperative consciousness grade,hematoma volume,bleeding location,preoperative time,glasgow score(glasgow coma score,GCS)at admission,mean arterial pressure(mean artery pressure,MAP)at admission,hematoma rupture into the ventricle,postoperative rebleeding,postoperative complicated pulmonary infection,postoperative complicated water electrolyte disturbance,history of diabetes,and other 13 factors,The glasgow outcome score(GOS)was used to evaluate the prognosis of patients at 3 months after operation,which was divided into poor prognosis group and good prognosis group.Single factor capital analysis measurement data were measured by t test and count data byχ2 test to analyze the correlation between these influencing factors and prognosis.The statistically significant influencing factors in univariate analysis were analyzed by multivariate logistic regression,and the statistical significance level was p<0.05.The rationality of this logistic regression model was evaluated using ROC curve(receiver operating characteristic curve).Results:Univariate analysis showed that age,hematoma volume,preoperative consciousness grade,admission GCS,preoperative time,rupture of ventricle,rebleeding after operation,pulmonary infection,poor prognosis related factors(P<0.05),while sex,admission MAP,history of diabetes had nothing to do with prognosis(P<0.05).Multivariate logistic regression analysis showed that GCS score,preoperative time,hematoma volume,rupture of the ventricle,rebleeding after operation and lung infection were independent risk factors for poor prognosis(P<0.05).Conclusion:Prognostic factors affecting minimally invasive treatment of HICH with puncture hematoma clearance are numerous and complex.The most significant of these factors are:GCS score,preoperative time,hematoma volume,rupture of the ventricle,rebleeding after operation and lung infection.We should aim at these factors in the clinical treatment of intervention for standardized treatment,as early as possible,early prevention,and timely treatment to improve the prognosis of patients.The area under ROC curve(AUC)of the multivariate binary Logistic regression model established in this study is 0.864,which indicates that it is reasonable.