Law Huoxuehuayu All α-blocker (Tamsulosin) In The Treatment Of Lower Ureteral Stones In Clinical Research

Objective:To evaluate the combined method huoxuehuayuα-blocker(tamsulosin) in the treatment of lower ureteral stones in clinical role.Methods:Study patients were from January 2008 -2009 onthe rule in March in Guangzhou University of Traditional Chinese Medicine First Affiliated Hospital of outpatient urology.52 cases will be eligible in accordance with the number of subjects were randomly divided into three groups form,in which men tamsulosin treatment group 10 cases,eight cases of women,average age 40.8±10.3 years old,the average maximum diameter of stone 6.6±2.1mm; promoting blood circulation to the treatment group 9 cases of men,9 women, average age 38.9±9.6 years old,the average maximum diameter of stone 6.9±2.3mm;Combined drug treatment group(Tamsulosin hydrochloride sustained-release capsules+huoxuehuayu side),nine cases of men and 7 women with mean age 39.7±10.5 years old,the average maximum diameter of stone 6.5±2.3mm;Three groups of patients with gender,age,the largest stone diameter by two independent samples t test,p＞0.05,comparable.①Tamsulosin group:Tamsulosin hydrochloride sustained-release capsules 0.2mg,1 times/day,oral.②huoxuehuayu side group:Jinqiancao 30g,Xiaoji 15g,Dongkuizi 15g, Trigonobalanus 10g,Ezhu 10g,rhubarb 10g,Reynoutria 20g,Radix Paeoniae Rubra 15g,Salvia miltiorrhiza 15g,Baimaogen 20g,Notoginseng 10g,cattle knee 15g,Radix Glycyrrhizae 6g,Lygodium 20g(pack fried),Neijin 10g,Plantago 20g,Wangbuliuxing 15g,decoction and taking.③Combined treatment group: Tamsulosin hydrochloride sustained-release capsules 0.2mg,ltimes/day, oral.Plus huoxuehuayu side groups:Jinqiancao 30g,Xiaoji 15g,Dongkuizi 15g, Trigonobalanus 10g,Ezhu 10g,rhubarb 10g,Reynoutria 20g,Radix Paeoniae Rubra 15g,Salvia miltiorrhiza 15g,Baimaogen 20g,Notoginseng 10g,cattle knee 15g,Radix Glycyrrhizae 6g,Lygodium 20g(pack fried),Neijin 10g,Plantago 20g,Wangbuliuxing 15g,decoction and taking. Three groups of patients are to encourage more drinking water and exercise, treatment for 6 weeks.Once a week follow-up visits,review of X-ray,Paishi record time,with or without the side effects of drugs,can tolerate.Stones from which to stop the treatment.After six weeks of no Paishi patients, according to the wishes of patients and patients decided to continue conservative treatment or ureteroscopy stone rubble.Results:The combined treatment group on the lower ureteral stones cure rate as high as 81.3%(13/16),Tamsulosin group was significantly higher than 50.0% (9/18) and blood group to 55.6%(10/18),statistical analysis with a statistically significant difference(P＜0.05).Three cases were cured Paishi time,thecombined treatment group in the lower ureteral calculi Paishi time of 6.23±1.21 days,Significantly shorter than tamsulosin group 9.87±1.55 days and blood group to 10.06±1.93 days,statistical analysis of significant difference(P＜0.01).All objects were 52 cases of clinical studies completed. Three groups of patients with clinical observations,blood circulation to group process in the treatment of two cases of patients with mild diarrhea, stool about 4 times/day,bad quality,no pain,but symptoms can persist after treatment to the end of the trial.The remaining patients did not appear to dizziness,rhinitis,diarrhea,abdominal pain,palpitations,skin rashes and other adverse reactions.Conclusion:The combined method huoxuehuayuα-blocker(tamsulosin) in the treatment of lower ureteral stones,can significantly shorten the waiting time stone to improve the cure rate,to enable patients to avoid the pain of surgery, thereby reducing the financial burden on patients,is an effective method of treatment,this method in the use of clinical urology,and better highlight the advantages of traditional Chinese and western medicine.