| Intestinal tract is one of the digestive organ,has the important effect to keep normal in nutrition of organism.The architectonic and function of intestinal mucosa will be injuried in the stringent state。after the operation, because of the damage of the intestinal mucosa,the patient will appear many symptoms,for exempal,abdominal distension,diarrhea,stomachache,debilitation,etc.The cause of appearing the symptoms is that after the operation patient occur damp-retention due to hypofunction of the spleen,or qi-stagnancy and blood stasis.according to that causes,we choose ShenLingBaiZhuSan and Dahuang to treat the patients.ShenLingBaiZhuSan and Dahuang could play the actions of invigorating the spleen,benefiting vital energy,dissipating dampness,checking diarrhea,and activating blood circulation to dissipate blood stasis.The pharmacological effects of some studies have showed that ShenLingBaiZhuSan and Dahuang has the function such as certainly antibacterial action,analgetic,anti-diarrhea and hemostasia, inhibit the intestinal mucosa damage,and enhance the body eliminate free radicals,andantioxidant capacity,regulate the disorder of immunity. Objective:Observe the improved situation ShenLingBaiZhuSan and Dahuang effects on intestinal mucosa damaged which belongs to damp-retention due to hypofunction of the spleen syndrome,or qi-stagnancy and blood stasis syndrome, and the reason from known or unknown causes the damage to the intestinal mucosa; study the relationship of Intestinal mucosa damage and dysbacteriosis;study ShenLingBaiZhuSan and Dahuang impacts on dysbacteriosis when intestinal mucosa is damaged.Methods:From May in 2007 to April in 2009,We have selectd 40 suitable Cases at inpatient department in Chinese medicine hospital in Guangzhou City,and divided in to two groups which were a treatment group(30cases) and a control group(30cases).The treatment group is supplied with PeV transfusion and ShenLingBaiZhuSan and Dahuang oral administration,each 100ml,twice a day, two weeks is aperiod of treatment.In contrast with the treatment group,the control group is only supplied with PeV transfusion,two weeks is aperiod of treatment.By observing the changes in biochemical indicator and prealbumin, observing the changes in symptoms,observing the changes in bacteria in patients with feces,observing the changes in gram-positive and negative bacteria and cocci and the ratio of change,observing the situation in bacterial culture in stool,and conducting before and after treatment with statistical analysis,then evaluation.All data wereanalysed with spssl3.0 sofware to compare the effect with the statistical resultsResults:(1) The first day after operation,biochemical indicator and prealbumin of the two groups were not obviously difference;the fourteenth day after operation,biochemical indicator of the two groups were obviously amelioration,but the treatment group and control group in effect were no significant difference(P＞0.05);the prealbumin of the two groups were obviously amelioration,and the treatment group and control group in effect were significant difference(P＜0.05).(2)The contrast with before and after treatment in Chinese medicine major symptoms core comparison,the difference in the two groups was significant statistical significance(P＜0.05),show that the two groups are effective treatment;the contrast with the two groups after treatment,the difference significant statistical significance(P＜0.05),show thatimprovement the main symptoms in Chinese medicine treatment group is better than the control group.(3)In Chinese medicine symptoms of the effects, the treatment group of Chinese medicine in the Comprehensive Clinical evaluation and symptoms are 90 percent efficient,control group of symptom and comprehensive assessment of Chinese medicine in the total effect of efficiency are 85 percent,show the total efficiency of the treatment group were higher than the control group,but after treatment the two groups were... |
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