The Study On Thetreatment Of Tan Re Yu Zu Non-Alcoholic Fatty Liver In China Taiwan Area By Qing Re Hua Tan Qu Yu Method

Background:Fatty liver disease (FLD) is a common clinical disease. it is always ignored as considered as obesity. In Taiwan the population of obesity, diabetes, and hyperlipidemia are gradually increased. The incidence of FLD showed a sharp upward trend. According to clinical statistics, the prevalence of non alcoholic fatty liver disease (NAFLD) patient was40.8%.almost in every three adults have one NAFLD and most of FLD patients are NAFLD, who maybe become liver fibrosis and cirrhosis, even the hepatoma. This symptom also arouse the medical scholars’attention. The disease imputes to Liver、Spleen、Kidney, its formation related to phlegm,dampness,blockage and plot,so we proposed the research of Qing Re Hua Tan Qu Yu method to treat the Tan Re Yu Zu Non-Alcoholic Fatty Liver patients in Taiwan District.Objective:According to traditional chinese medicine theory and clinical experience, combined with modern medicine.To observe the clinical effect of Qing Re Hua Tan Qu Yu method, and to be combined with liver function, renal function, lipid metabolism, blood routine examination, other laboratory tests and B ultrasound scan, to discuss the function and treatment effect.Methods:The reserach studies on80NAFLDs who are diagnosed as Tan Re Yu Zu NAFLD,adopted random allocation principle,divided the qualified cases into two groups:one treatment group of40patients, another control group of40patients.Two groups all have the basic treatment.The composition of TCM herbs in treatment group are listed as below:chao-dang-sen10g, chai-hu10g, chao-bai-zhu10g, fu-ling10g, gua-lou10g, dan-senlOg, huang-zin10g, chui-pen-cao10g, chi-shao10g, bai-shao10g, ze-xie10g, sheng-shan-zha10g, uan-hu-suo10g, di-bie-chong10g, shui-zhi6g, boiled with water,one day one package,drink two times per day,one course for3months.The control group:taking the rosuvastatin lOmg/d for3months. The observing indexes include:age, sex, weight, liver function,renal function,lipid metabolism,blood routine examination, B ultrasound scan and clinical symptom score, the differences between two groups has no significant meaning(p>0.05), two groups have comparability.Results:1. Total effective rate of treatment group is85.0%, the total effective rate of control group is72.5%, both of the two groups have significant difference (p<0.05).It means the effect of treatment group is better than that of control group.2. After treatment,it has significant differences in clinical symptom score between two groups(p<0.05),the effect of treatment group is better than that of control group. Both of them can improve clinical symptoms obviously,there is a significant difference (p<0.05).The treatment group shows improvement,in chest pain, in listlessness and lassitude, in thirsty and bitter, in gloomy complexion,in chest tightness, in sleep, in tongue and sublingual blue veins, the comparsion has significant meaning (p<0.05).3. After treatment, both groups in liver function (AST, ALT, ALP, y-GT) have significant difference (p<0.01). The treatment group has better effect than the control group in liver function index (AST, ALT, ALP, r-GT)(P<0.05).4. After treatment, both groups in lipid metabolism (TC, TG, HDL-C, LDL-C) have significant difference (p<0.01). The treatment group has better effect than the control group in lipid metabolism (TG, HDL-C, LDL-C)(p<0.05). Both groups are closely in effect of TC.Conclusion:The effect of treatment group in Tan Re Yu Zu NAFLD is better than that of control group.