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The Correlation Research Between Deffating Of Overweight Middle-aged In Walking Exercise Intervention The ADPN Polymorphism

Posted on:2010-09-02Degree:DoctorType:Dissertation
Country:ChinaCandidate:X X LiFull Text:PDF
GTID:1227360275963792Subject:Human Movement Science
Abstract/Summary:PDF Full Text Request
Objects:The paper is to find out how gene polymorphism sign follows the genovatiation and which genetype is more sensible to exercise,by exploring the relation between walking exercise,BIM,body constit, blood bodymeasure,and phenotype,also with the connection between PPARγ2 gene,adiponectin,and gene adipose cell factor being considered, thus to offer the theoretical basis for individualization exercise prescription of the old and the molecule signalMethod:By survey investigation and health examination,92 person(aged between 50-65),including fracture-type and adipositas-type,are choosen and randomly divided to EG(70) and CG(22).According BMI,those with BMI≥25 being adipositas,those with 23≤BMI<25 being overweight.By taking the maximal cycle ergometer exercise,their functional capacity(F.C) and target heart rate are to be determined.It is set that the exercise intensity is 40%-50%F.C.-50%-65%,the efficient time of FC is 40min/once, exercise frequency is 5times/week,the exercise circle is 3months,all of which is to interview the connection between phenotype and gene polymorphism sign.CONCLUSIONS:1.walking Exercise can significant decrease the body fat,BIM, weight,WHR,WC,ABSW and FFA of overweight- group and obesity- group.2.walking Exercise is a in effect method which can decrease the fat%,blood fat of the obesity people and increase the ADPN level, improve body measure index of the old fat people,3.The correlation research between aerobic walking interfering the fat of the old and the APM-lgene T45G polymorphism shows,TT gene type have a independence correlation with BMI,weight,TC,LDLC.While TG gene type have a independence correlation with fat%,and ADPN.thus TT、 TG gene type are capable of being the sensitive gene signal of exercise,while it seems the principle of APM-1 geneG276 polymorphism’ s change is the same as that of T45G.After exercise,GT gene have a independence correlation with BMI,weight,fat%,TC,and LDLC,thus GT gene type are capable of being the sensitive gene signal of exercise as estimation defatting4.The correlation research between aerobic walking interfering the fat of the old and the PPARγ2 Pro12Ala polymorphism shows,CC gene type have a independence correlation with BMI,weight,TC,LDLC.The PPARγ2 C161T polymorphism shows,CC gene type have a independence correlation with blood fat,ADPN,FFA,thus CC gene type are capable of being the sensitive gene signal of exercise as estimation blood,body quality guideline...
Keywords/Search Tags:overweight, walking exercise, middle-aged, Adiponectin, PPARγ2, polymorphis
PDF Full Text Request
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