Analysis Of Professor Guo Enmian's Medication Rules In The Treatment Of Chronic Renal Failure Based On Data Minin

Objective: To study Professor Guo Enmian’s medication rules for treating chronic renal failure with traditional Chinese medicine through the method of data mining,in order to obtain new knowledge,new data and new information based on medical records.Promote and better serve patients.Materials and methods: In this study,through clinical follow-up records and access to the outpatient medical record system,the cases of patients who met the diagnostic criteria of chronic renal failure at the Guo Enmian Ming-Ming TCM Studio of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 2018 to November 2021 were collected.The cases were screened according to the inclusion criteria,and 106 effective prescriptions were determined.The Excel function was used to classify the drugs,and the IBM SPSS Statistics 26 was used to perform cluster analysis on the drugs.Research result:1.Among the 106 patients with chronic renal failure collected in this study,there were 58 males and 48 females,with a male-to-female ratio of 1.2:1.The number of patients over 35 years old was the largest,accounting for 90.57%.2.A total of 130 flavors of traditional Chinese medicine were involved,with 1864 frequencies.There are 34 kinds of medicines that have been used for 14 times or more.The top 15 Chinese medicines are: Astragalus,Atractylodes,Dodder,Cornus,Taizishen,Rhubarb,Perlan,Amomum,Lycium barbarum,Golden Cherry,White Cardamom,Salvia,Cicada slough,Alisma,Zelan.3.There are 16 types of medicines involved,and the top 8 medicines are tonic medicines(32.73%),dampness-removing medicines(17.81%),astringent medicines(11.37%),heat-clearing medicines(8.21%),and detoxifying medicines(8.21%).Medicines(5.58%),laxatives(5.36%),diuresis and dampness medicines(4.29%),blood-activating and stasis-removing medicines(3.92%).Among the tonic medicines,qi and yin medicines are the main ones.4.In the statistics of drug meridians,the most drugs belonged to the spleen and kidney meridians;in the statistical analysis of the four qi,the most used medicines were flat medicines,followed by(slightly)warm and(slightly)cold medicines.It is used the most,followed by(slightly)bitter and(slightly)pungent herbs.5.Through the cluster analysis and association rule analysis of the prescriptions used by Professor Guo Enmian,we obtained Astragalus & Taizishen,Astragalus & Atractylodes,Dodder & Cornus,Keel & Oyster,Salvia & Zelan,Cicada Slough & Silkworm,Patchouli &Alisma,Hedyotis diffusa & Rhizoma Imperatae,Astragalus & Dodder & Cornus,Astragalus& Atractylodes & Dodder,Astragalus & Atractylodes & Taizishen etc.And explored 4groups of cluster medicine groups,namely Astragalus,Dodder,Cornus,Taizishen,Atractylodes,Lycium barbarum,Jinyingzi,Salvia,Zelan,Rhizoma Imperatae,Hedyotis diffusa,Tuckahoe;Rhubarb,Peilan,Alisma,Amomum,Patchouli,Cardamom;Cicada Slough,Polygonatum,Gorgon,Eucommia,Silkworm,Arctium,Coptidis,Bupleurum,Asparagus,Dog Chi and Oyster,Keel,Gastrodia,Cassia.conclusion:1.Professor Guo Enmian believes that chronic renal failure is a symptom of deficiency and excess.The disease location is mainly in the spleen and kidney,and deficiency of both qi and yin is more common."Deficiency of the spleen and kidney,and diffuse dampness,turbidity and toxins" is the key to its pathogenesis.2.Professor Guo’s treatment of chronic renal failure is based on the spleen and kidney,and the treatment is based on the spleen and kidney.The treatment principle of "replenishing deficiency and eliminating pathogens,attacking and nourishing simultaneously" is put forward,and the core treatment method is "replenishing spleen and kidney,nourishing qi and nourishing yin,removing blood stasis and clearing heat,dispelling dampness and expelling toxin".