Clinical Observation On The Therapeutic Effect Of Modified Wuwei Xiaodu Decoction Combined With Sihuang Ointment For External Use In The Treatment Of Low Anal Carbuncle With Fire Poison Accumulation

Objective:To observe the clinical efficacy of the combination of five-flavored disinfectant drink with four-huang ointment in the treatment of low-level canker sores caused by fire toxicity.Methods:Seventy-two patients diagnosed with fire poisonous canker sores were divided into a treatment group and a control group of 36 patients each according to the random number table method.In the treatment group,the patients were given Gao Wei Wu Wei Disinfectant Drink orally combined with Si Huang Ointment externally,while in the control group,the patients were given Cefdinir capsule orally combined with Mupirocin Ointment externally for a period of 7 days.The clinical efficacy was evaluated by analyzing and comparing the clinical symptoms,TCM syndrome points,signs,inflammation indexes and pus ulceration rate of the two groups.Results:This study shed and eliminated 7 cases,and 65 patients finally completed the study,treatment group(N=33)and control group(N=32).There was no significant difference(P>0.05)in general condition,disease duration,abscess location,perianal pain index,skin temperature,mass size range,white blood cell count,CPR,and calcitonin between the two groups of cases before treatment in a balanced comparison,which was comparable.1.Clinical efficacy:The total effective rate of the treatment group was(81.82%)higher than that of the control group(65.63%),and the difference was statistically significant(P=0.010<0.05).2.Symptoms and signs:by rank sum test,anal pain after treatment:control group(3.03±1.00)points,treatment group(2.39+0.97)points,P=0.014<0.05;local skin temperature:control group(0.47±0.51)points,treatment group(0.21 ±0.42)points,P=0.03<0.05;using two independent samples t-test,mass range:control group(2.06±0.74)cm,treatment group(1.56±0.93)cm,P=0.01<0.05.It indicates that the symptoms and signs of patients in both groups have improved after treatment,and the improvement effect of the treatment group is better than that of the control group.3.Total TCM points:control group(14.91 ±6.23)points,treatment group(8.55±6.55)points,P=0.000<0.05.After treatment,the total TCM points of both groups decreased compared with those before treatment,and the total TCM points of the treatment group decreased significantly.4.Self-rupture rate:There were 9 cases of self-rupture in the treatment group,with a self-rupture rate of 27.27%,and 2 cases of self-rupture in the control group,with a rupture rate of 6.25%.The comparison between groups,P=0.024<0.05,indicates that the treatment group has better efficacy than the control group in promoting self-rupture of abscess.5.Incision and drainage rate:6 cases needed incision and drainage after treatment in the treatment group,with incision and drainage rate of 18.18%,while 13 cases needed incision and drainage in the control group,with incision and drainage rate of 40.62%.The comparison between groups,P=0.047<0.05,the efficacy of the treatment group in reducing the incision and drainage rate of abscess was more significant than that of the control group.Conclusion:The combination of oral addition of Wu Wei Disinfectant Drink with Si Huang Ointment was effective in relieving perianal pain,reducing the size of the mass,promoting abscess collapse,incision and pus discharge rate in patients.