| Objective: To observe,study and explore the clinical efficacy and safety of the treatment of female acne with Chongren disordered syndrome based on Danzhi Xiaoyao powder,in order to provide new ideas and methods for the treatment of female acne.Methods: In this study,72 cases of female acne patients with Chongren disorder in outpatient department of our hospital were selected as samples,which were collected from November 2021 to November 2022.Random number table method was used,the patients eligible for inclusion were divided into experimental group and control group.The experimental group was given oral Danzhi Xiaoyao powder plus or minus,150ml/ time,2times/day,and the control group was given oral tanshinone capsules(1g/ capsule),4capsules/time,3 times/day.Both groups were treated with 30% supramolecular salicylic acid,once every 2 weeks.4 weeks is a course of treatment.After 0,1,2,3 and 4 weeks of treatment,the main lesion score,TCM secondary disease score and skin disease life quality index score were respectively performed in the two groups.The recurrence situation and adverse reactions were observed and recorded,and the data were statistically analyzed by SPSS26.0.Blood,urine,fecal routine and liver and kidney function tests were performed before and after treatment in the two groups.2 months after treatment,one follow-up was conducted to observe the total effective rate and recurrence rate.Results:1.Completion: A total of 72 cases meeting the criteria were collected in this study,among which 2 cases were eliminated and 1 case was shed in the experimental group,and33 cases were actually effective;In the control group,1 case was eliminated and 1 case was shed,with 34 effective cases.The total number of effective cases was 67.There was no statistical significance in general data between the two groups before enrollment(P >0.05),indicating comparability.2.Clinical efficacy: After the course of treatment,the total effective rate of the experimental group was 93.94%,and that of the control group was 70.59%.After testing,the difference between the two groups was statistically significant(P < 0.05),indicating that the curative effect of the treatment group was better than that of the control group.3.DLQI score: After the course of treatment,DLQI of experimental group and control group was compared,P < 0.05,the difference was statistically significant,and the improvement of DLQI of experimental group was significantly better than that of control group.4.Score of major lesions: After the treatment course,the number,color,texture and pain degree of the two groups of patients were compared.The two methods were effective for all the symptoms of the skin lesions(intra-group comparison P < 0.05),and the two methods were equally effective for the texture and pain degree of the skin lesions(inter-group comparison P > 0.05).The efficacy of the experimental group was better than that of the control group in terms of the number and color of lesions(P < 0.05),and the comprehensive efficacy of the experimental group was better than that of the control group in terms of the main lesions(P < 0.05).5.TCM sub-disease score: After the course of treatment,the scores of the three TCM subdisorders of the two groups of patients were compared.The two methods were effective for all TCM subdisorders(intra-group comparison P < 0.05),and the efficacy of the two methods was equivalent for irritability and irritability(inter-group comparison P >0.05).The efficacy of the experimental group was better than that of the control group for breast tenderness and irregular menstruation(inter-group comparison P < 0.05),and the comprehensive efficacy of the experimental group was better than that of the control group for TCM sub-disorders(inter-group comparison P < 0.05).6.Recurrence rate: After the course of treatment,the behavioral stage of the two groups of patients was followed up for 2 months,and the recurrence rate of the experimental group and the control group was compared,P < 0.05,the difference was statistically significant.The recurrence rate of the experimental group was 15.15%,which was significantly better than 38.24% of the control group.7.Adverse reactions: No adverse reactions occurred in the two groups after the course of treatment,and no abnormalities were found in the auxiliary examination results.The safety of the two treatment methods was good.Conclusion:1.Based on the time rhythm Danzhi Xiaoyao powder addition and reduction treatment Chongren irregular syndrome of female acne efficacy is better than oral tanshinone.2.Based on the time rhythm Dan Zhi Xiaoyao powder addition and reduction for improving Chong Ren irregular syndrome of female acne patients with skin lesions,Chinese medicine,dermatosis life quality index efficacy are better than oral tanshinone.3.Based on the time rhythm Dan Zhi Xiaoyao powder addition and reduction treatment Chongren irregular syndrome of female acne clinical efficacy,good safety,low recurrence rate,worthy of clinical promotion and application. |
PDF Full Text Request