Clinical Study On The Treatment Of PCOS Dyslipidemia Due To Spleen Deficiency And By Spleen Deficiency And Phlegm Dampness By Combining Acupuncture And Medicine

Objective: To observe the clinical efficacy of the combination of acupuncture and medicine in the treatment of dyslipidemia in polycystic ovary syndrome(PCOS)due to spleen deficiency and phlegm dampness,and to explore the mechanism of its efficacy,so as to add new ideas and methods for the treatment of this disease.Methods:Using a randomized controlled study method,70 eligible patients with PCOS dyslipidemia due to spleen deficiency and phlegm-dampness were randomly divided into an acupuncture-medicine group with 35 cases and a traditional Chinese medicine group with 35 cases.The acupuncture-medicine group was treated with acupuncture combined with Jianpi Huatan Decoction,and the traditional Chinese medicine group was treated with Jianpi Huatan Decoction for 3 months.The changes of body mass index(BMI),waist-to-hip ratio(WHR),serum sex hormones,clinical comprehensive efficacy,TCM syndrome scores,and blood lipid index levels in the two groups were observed.Statistical methods were used to analyze the data of the two groups and draw conclusions.To evaluate the clinical efficacy of the combination of acupuncture and medicine.Results:1.A total of 70 patients were included in the two groups,35 patients in the acupuncture group,34 completed,and 1 dropped;35 in the traditional Chinese medicine group,31 completed,4 dropped,and the dropout rate was7.14%.2.Analysis of total clinical curative effect: After 3 months of treatment,the total curative effect rate of the acupuncture group was 85.29%,and that of the traditional Chinese medicine group was 61.29%.The comparison between the two groups was P=0.021,and the difference was statistically significant(P<0.05),indicating that the total curative effect of the acupuncture-medicine group was significantly better than that of the traditional Chinese medicine group.3.The efficacy of TCM syndromes: After 3 months of treatment,the efficacy of TCM syndromes in both groups were improved compared with those before treatment(P<0.05).).(4)WHR: After treatment,the WHR of the acupuncture-medicine group was significantly improved(P<0.05),while the WHR of the traditional Chinese medicine group was not significantly improved(P<0.05).4.BMI: After 3 months of treatment,the BMI of the two groups was significantly improved(P<0.05),and the acupuncture-medicine group was significantly improved compared with the traditional Chinese medicine group(P<0.05).5.WHR:After 3 months of treatment,the WHR of the two groups were significantly improved(P<0.05),and the acupuncture group was significantly improved compared with the traditional Chinese medicine group(P<0.05).6.Serum sex hormones: After treatment,T,LH,LH/FSH in the two groups were significantly improved(P<0.05);and the improvement in the acupuncture group was better than that in the traditional Chinese medicine group(P<0.05);There was no improvement before(P>0.05),and there was no statistical difference between the two groups(P>0.05).7.Blood lipid indexes(TG,TC,HDL-C and LDL-C): after 3 months of treatment,TG,TC,HDL-C and LDL-C in the two groups were improved compared with those before treatment(P<0.05);TG,TC in the acupuncture group after treatment The improvement of HDL― C was better than that of the traditional Chinese medicine group(P<0.05);there was no significant difference in the improvement of LDL-C between the two groups after treatment(P>0.05).Conclusion:(1)Pure traditional Chinese medicine Jianpi Huatan Decoction can improve the dyslipidemia of PCOS due to spleen deficiency and phlegm dampness.(2)On the basis of simple traditional Chinese medicine,combined with acupuncture and moxibustion in the treatment of spleen deficiency and phlegm-dampness type PCOS dyslipidemia will have better curative effect,and it is worthy of further discussion and promotion in clinical practice.