The Historical Research Of The Formula Preparation Of The Ming Dynasty

Dosage form is an important content in the study of prescriptions.In the song and Yuan Dynasties,there was basically a complete system.On the basis of inheriting the achievements of the previous generation,the medical theory and practice of Ming Dynasty kept innovating.In order to further improve the history of dosage forms,this research adopts the methods of philology and history,combining internal and external history,and takes Ming Dynasty prescription books,clinical medical books and herbal works as the research objects to sort out the relevant historical materials of prescription forms,classify,count and analyze them respectively,so as to understand the basic features of the development of dosage forms in the Ming Dynasty.Decoction,pill,paste and powder were the main formulations used in Ming Dynasty.Compared with song and Yuan dynasties,the application of medicinal liquor,pastilles and coated pills increased.Cut decoction pieces rose in the Ming Dynasty,and physicians’ further understanding of the dosage form selected based on syndrome differentiation made boiling agent the main application of decoction.The application of "dregs Decoction"is more extensive,and lishizhen and others have supplemented the theory.The increasing use of Shaojiu has promoted the transformation of medical liquor from low concentration liquor to high concentration liquor.Due to the comprehensive and rapid development of surgery in Ming Dynasty,the external dosage forms represented by oil were further developed.In the Ming Dynasty,the pill making technology was in the hands of businessmen and businessmen,and there were many advances in the processing of pills:①the preparation method of soaking for several days appeared;②Pill drying;③While pill coating is widely used,the types of coating materials are increasing.There are about hundreds of excipients in pills,and the efficacy of excipients is used as the selection standard.The external use of pills has been expanded.In addition,the technology for preparing powder is more mature.Suppository and other dosage forms can be reused.Lishizhen has established the application of "removing fire poison" in the paste making process theoretically and practically,and has been widely used in oral cream,ointment and hard cream.There are two plasters superimposed and used.Pay attention to usage:①the types of mounting materials increase;②Cut holes of mounting materials to vent air;③Emphasize the thickness of the paste;④Emphasize washing;⑤Acupoints are added to the spreading and pasting part;⑥The usage of spreading and pasting is more extensive.Plaster rubbing and ironing is an important external treatment for internal injury.Wu Kun pointed out that gas dosage forms exert their efficacy through"respiratory transmission".Smelling agents are mostly used for Qi inversion syndrome,critical syndrome.It is an important supplement to internal therapy through drug Qi therapy.The prosperity of decoction pieces in the Ming Dynasty was the result of multiple factors.The stability of government,the development of commodity economy,the innovation of processing tools and theory and technology,and the further understanding of physicians on the selection of dosage forms based on syndrome differentiation were all important driving forces.Pre moisten the medicinal materials.Common methods of "removing fire poison" include water immersion method,burying method,placing in a cool wetland method,etc.At that time,the preparation technology of liquor and paste had taken the rudiment of modern preparation technology.Pay attention to the clinical reuse of drug residues after preparation.Some prescriptions in Ming Dynasty had the application of"one prescription with two forms".There were various preparation moulds in Ming Dynasty.The system and types of prescriptions in the Ming Dynasty were further enriched and enriched on the basis of the song,Jin and Yuan Dynasties.The preparation process is more refined,focusing on the administration and storage of dosage forms.The clinical application scope and use methods of dosage forms are expanded,and the theory of prescription dosage forms is comprehensively inherited and deepened.