| Objective:The classic prescription Banxia Xiexin Decoction of "Treatise on Febrile Diseases" is a representative prescription for the treatment of the syndrome of cold and heat in the middle Jiao,which has a wide range of clinical applications and excellent curative effect.This research uses it to study the theory of prescriptions and syndromes,and intends to use modern data mining statistical techniques and methods.Based on the clinical records of Banxia Xiexin Decoction,a physician in the Qing Dynasty,to explore the characteristics of the prescriptions and syndromes of this prescription,in order to provide theoretical knowledge for the clinic.And application ideas.Contents and Methods:The full text is divided into four chapters.Literature review:Document the modern clinical application and experimental research of Banxia Xiexin Decoction,write a literature review,and understand the modern research progress of this prescription.Chapter One examines the origin of Banxia Xiexin Decoction.Based on the content of the original text,prescription composition and decoction method described in different editions of "Treatise on Febrile Diseases" and "Synopsis of the Golden Chamber",a comparative analysis is made.The second chapter studies the prescription theory of Banxia Xiexin Decoction.Including the etiology and pathogenesis,symptom analysis,disease location analysis and prescriptions compatibility,as well as the supplementary content of the syndromes and symptoms,tongue and pulse conditions,abdominal syndrome and other prescriptions.At the same time,they have a deep understanding of the relevant literature of Banxia Xiexin Decoction "Fanghou Note" And carry out the identification of the class party and party certificate.Chapter Three:Research on the rule of syndrome and treatment of Banxia Xiexin Decoction based on Qing Dynasty medical records.Through the "Chinese Medical Dictionary" medical records,medical records,typhoid syndrome,internal medicine,and clinical comprehensive literature content,the Qing Dynasty medical records to be checked are initially formed,and the collection of books,superstar readers,ancient and modern medical records cloud The platform,Chinese medicine database,etc.supplemented the data,and according to the inclusion and exclusion criteria,a comprehensive collection of clinical medical records of the Qing Dynasty doctors using Banxia Xiexin Decoction.Using data mining technology and methods,statistical analysis is carried out through Microsoft Excel 2019,ancient and modern medical records cloud platform(V2.2.3),and SPSS 23.0 software.conclusions:(1)The Song version of "Treatise on Febrile Diseases" and Deng Zhen’s" Synopsis of the Golden Chamber" record the most complete and standard contents.(2)Banxia Xiexin Decoction carries out theoretical research on prescriptions and syndromes,fully demonstrating the diagnosis and treatment characteristics of TCM clinical"different diseases with the same treatment".The etiology of this prescription can be different from external feelings and internal injuries;the pathogenesis is yin and yang imbalance,cold and heat,and both deficiency and excess.Disharmony of qi,abnormal qi movement,invisible qi and tangible evil;disease stage can be in the spleen,stomach and gall bladder,triple energizer,half surface and half inner,diaphragm,Jueyin and Wei Qi Yingxue Qi points;Indications Symptoms include fullness,diarrhea,gonorrhea,swelling,malaria,epigastric pain,choking,summer heat,and dampness.In addition to vomiting,bowel irritation,and hypocardia,later physicians have added chills,Retching,yellowing,chest and diaphragm pain,epigastric pain,nausea,upset,insomnia,noisy,soreness,mouth pain,abdominal pain,intermittent constipation,etc;The main pulse is Ruo,Rushu,Shen,Shen Xian and smooth or weak;the tongue coating is yellow and greasy,thick and greasy or slightly yellow and greasy,and the tongue is white and light yellow;the abdominal syndrome is mainly sub-heart ruffles(fullness).Inverse qi is vomiting,while drinking in the abdomen will cause bowel sounds and lowering,stop water in the stomach,tapping to make the sound of water vibration;when decoction should be covered,decocted before decoction;seaweed and drop vegetable soup are not allowed during medication,Lamb,raw onion,pork,cold water and other fishy,greasy,hot and difficult to digest things.(3)The application rules of Banxia Xiexin Decoction recorded in Qing Dynasty include:through modern statistical analysis of relevant documents,it was found that the etiology of Banxia Xiexin Decoction was mostly related to summer pathogens,seven emotions,internal injuries and mistreatment;Symptoms include malaria,fullness,vomiting,typhoid fever,choking,etc.;the tongue is white or yellow,or the side is red or prickly,and the tongue coating is mostly greasy;the main pulse conditions are string,number,and astringency;the core main symptoms are Abdominal lumps,vomiting,nausea,loose stools,fever,thirst,anorexia,difficulty having a bowel movement,epigastric pain,chest pain,chills,abdominal pain,abdominal distension;this can be combined with Wendan Decoction,Xuanfu Daizhe Decoction,and Aconite Xiexin Decoction,Da Banxia Decoction,Wuling San and Sini San are used in combination;the most flavored medicine is Zhishi.Through the analysis of association rules,it is found that fever or thirst are associated with epigastric pain,loose stools are associated with appetite,nausea,fever,and thirst are associated with subcardiac diarrhea,nausea and difficulty having a bowel movement are associated with vomiting,subcardiac diarrhea,Vomiting,and loose stools can be used as independent symptom indications for the use of Banxia Xiexin Decoction.Through cluster analysis,the syndrome of Banxia Xiexin Decoction must use Pinellia and Coptis,and the vomiting must use Pinellia;the syndrome of Banxia Xiexin Decoction is closely related to the selection of Pinellia and Coptis;Ginseng,Citrus aurantium,Citrus aurantium,Dried ginger,pinellia and coptis may be commonly used addition and subtraction prescriptions for Banxia Xiexin Decoction.Conclusion:In this study,research on the origin of Banxia Xiexin Decoction and the theory of prescriptions and syndromes,and through statistical analysis of medical records based on the clinical literature of the Qing Dynasty,expand the relevant issues of Banxia Xiexin Decoction,supplement and perfect the Banxia Xiexin Decoction Proof of research content.It provides reference for modern traditional Chinese medicine prescriptions,as well as guidance and enlightenment for clinical use. |