| Objective: Analyze and explore the improvement of symptoms in patients with Chronic Fatigue Syndrome after modified snake moxibustion combined with acupuncture,and to clarify the clinical advantages of modified long snake moxibustion in the treatment of CFS,so as to develop a simple and effective moxibustion scheme for CFS patients from two aspects of single moxibustion time and treatment course.Methods: From March 2015 to April 2020,a total of 584 CFS subjects were included in the preventive treatment center of Sichuan Provincial Hospital of traditional Chinese medicine.According to different early intervention methods,the subjects were divided into 90 min / 60 min / 45 min modified snake moxibustion group and ordinary acupuncture group.According to the improvement of fatigue severity scale(FSS),the dependent variables were divided into three groups: markedly effective group,effective group and ineffective group.According to the specific clinical symptoms represented by the other six groups of recognized standard scale items,they were divided into four groups: general physiological function,somatic feeling,mental and emotional health,and social life.The improvement values before and after treatment were taken as independent variables,namely,the patient’s basic situation and TCM Syndrome scale,physical and mental health report(sphere),self rating Anxiety Scale(SAS),self rating Anxiety Scale(SAS)Self rating Depression Scale(SDS),Hamilton Anxiety Scale(HAMA),health status questionnaire(SF-36)and other six standard scales.SPSS 25.0 software was used for ordinal logistic regression analysis,generalized estimation equation,and decision tree and path analysis chart were formed to compare the difference of the influence of the improvement of clinical symptoms on the overall efficacy of the four groups with different time length intervention,and to explore the relationship between the treatment course and the overall efficacy of each group,From the time of single moxibustion and the course of treatment,this paper analyzes the specific situation of improved snake moxibustion in improving the main clinical symptoms of CFS,clarifies the advantages of the four groups of intervention methods,and designs the moxibustion scheme.Results: 1.Duration of single Moxibustion: the general physiological function,emotion,mental health and physical feeling of the ordinary acupuncture + 90 min modified snake moxibustion group were significantly improved(P < 0.05),and the influence order of each factor was emotion and mental health,physical feeling and general physiological function,and the former two had significant positive effect on the general physiological function of patients(P < 0.05).After regression analysis,there was no statistical significance in all factors in the ordinary acupuncture + 60 min modified snake moxibustion group;The general physiological function and social life were the independent influencing factors;The decision tree indicated that the order of influencing factors was emotion and mental health,body feeling and general physiological function;Path analysis showed that emotion and mental health had the most significant effect on the curative effect(P = 0.01 < 0.05);The improvement of social life had a negative impact on the overall efficacy(P = 0.091 < 0.1).Due to the small sample size of this group,the overall representativeness is poor,and the results need to be further verified.The general physiological function,emotion and mental health of the ordinary acupuncture + 45 min modified snake moxibustion group were significantly improved(P < 0.05),and the influence order of each factor was emotion and mental health,general physiological function.The general physiological function of patients in the ordinary acupuncture group was significantly improved(P < 0.05).Overall efficacy: ordinary acupuncture + 60 min modified snake moxibustion > ordinary acupuncture + 90 min modified snake moxibustion > ordinary acupuncture + 45 min modified snake moxibustion > ordinary acupuncture(because the sample size of 60 min group is small,the overall representativeness is poor,the results of this group need to be further verified).2.treatment course: except for the modified snake moxibustion group for 60 min,the p value of the repeated score time of each group was lower than 0.05,and the coefficient was > 0,or > 1.The effect was gradually significant with the treatment time.The first scale evaluation(i.e.two weeks after treatment and six treatment)and or value were multiple of the later scoring time,and the most significant improvement was achieved in the two weeks.In addition to 45 min group,P > 0.1 was obtained in each follow-up period,and the effect remained stable;When moxibustion was 45 minutes,the first follow-up effect decreased(or > 1),and the effect decreased,but the later follow-up effect did not change significantly(P > 0.1).Conclusions: 1.Modified snake moxibustion combined with acupuncture can improve the clinical symptoms of CFS patients;2.The duration of single moxibustion was directly proportional to the degree of symptom improvement,and the clinical effect of 90 min modified snake moxibustion was the most comprehensive and significant.3.The shortest effective course of treatment was 2 weeks,and the longer the intervention time,the more stable the curative effect... |
