Modified Yinchenhao Decoction Combined With Compound Acid In The Treatment Of Spleen Stomach Damp Heat Acne

Objective The modified Yinchenhao Decoction Combined with compound acid(composition:24% salicylic acid,6% almond acid)was used to treat spleen stomach damp heat acne.The changes of skin lesion severity,symptoms,signs and quality of life were observed,and its efficiency and safety were evaluated to provide basis for clinical treatment of acne.MethodIn this study,90 patients with spleen stomach damp heat acne were randomly divided into three groups.The treatment group was treated with modified Yinchenhao Decoction Combined with compound acid;Control group 1: treated with modified Yinchenhao Decoction;Control group 2: treated with compound acid.The observation indexes of each group were scored and recorded before,during and after treatment.The data were statistically analyzed by spss25.0 software.Result1 GAGS score resultsAt the end of the 4th and 8th weeks of treatment,there was significant difference between the treatment group and the two control groups((49)<0.05),and there was no significant difference between the two control groups((49)>0.05);Intra group comparison:there was significant difference at each time point before and after treatment in the same group((49)<0.05).2 TCM syndrome score resultsAt the end of 4 weeks of treatment,the improvement of TCM syndromes in the treatment group was better than that in the two control groups,with statistical difference((49)<0.05),and that in the control group 1 was better than that in the control group 2((49)<0.05);At the end of 8 weeks of treatment,the improvement of syndrome in the treatment group was better than that in the control group 2((49)<0.05),and there was no significant difference((49)>0.05)compared with the control group 1.There was a difference between the control group 1 and the control group 2((49)<0.05);The three groups were compared within the group,and there were significant differences((49)<0.05).3 Quality of life scoreAt the end of 4 weeks of treatment,the improvement of quality of life in the treatment group was better than that in the control group 2((49)<0.05),and there was no significant difference((49)>0.05)compared with the control group 1.There was no difference((49)>0.05)between the two control groups;At the end of 8 weeks of treatment,the treatment group was better than the two control groups,with statistical difference((49)<0.05),and the control group 1 was better than the control group 2((49)<0.05);The three groups were compared within the group,and there were significant differences((49)<0.05).4 Efficacy evaluation resultsComparison of skin lesion efficacy: after treatment,the cure rate and effective rate of the treatment group were better than those of the two control groups((49)<0.05),and there was no significant difference between the two control groups((49)>0.05).Comparison of TCM syndrome efficacy: after treatment,the cure rate and effective rate of treatment group and control group 1 were better than that of control group 2((49)<0.05),but there was no significant difference between the first two groups((49)>0.05).Comparison of comprehensive efficacy: after treatment,the cure rate of the treatment group was better than that of the two control groups((49)<0.05),and there was no difference between the two control groups((49)>0.05);The effective rates of treatment group and control group 1 were better than those of control group 2((49)<0.05).5 Adverse reactionsDuring the treatment,patients in treatment group and control group 2 had mild irritation during acid brushing,which did not affect the treatment.All patients taking traditional Chinese medicine did not suffer from discomfort.There were no abnormalities in liver and kidney function and hematuria before and after treatment in the three groups.6 Comparison of recurrence rateOne month after the end of treatment,the number of recurrent cases in the three groups was 1,1 and 5 respectively.There was significant difference between the treatment group and the control group 2((49)<0.05),but there was no difference between the treatment group and the control group 1((49)>0.05),There was significant difference between the control group 1 and the control group 2((49)<0.05).Conclusion1.The clinical efficacy of modified Yinchen Hao decoction combined with compound acid in the treatment of dampness-heat acne of spleen and stomach is satisfactory,which can significantly improve the skin lesions,symptoms,signs and quality of life of patients.2.No serious adverse reactions occurred in all patients participating in this project during the treatment,and the safety is worthy of affirmation.