Analysis Of The Correlation Between The Blood Lipid Level During Pregnancy And Pregnancy Outcome In Patients With Hypertensive Disorders Of Pregnancy

Objective The purpose of this study is to investigate the blood lipid level of pregnant women with hypertension during pregnancy,and the correlation with blood pressure level and adverse pregnancy outcomes,so as to provide effective intervention measures for patients with hypertension during pregnancy and reduce adverse maternal and infant outcomes.Methods We retrospectively selected pregnant women and their newborns who had undergone pregnancy check-ups and gave birth in the obstetrics department of Gansu Provincial People’s Hospital from January 2019 to January2021 as the research objects.Among them,a total of 166 cases of pregnant women with hypertension in pregnancy were in the HDP group,and the normal group was in the HDP group.87 cases of pregnant women with normal blood pressure who gave birth during the same period of obstetric examination;analyzed the general clinical baseline data of pregnant women,their blood lipid levels during pregnancy,and pregnancy outcome.According to the severity of blood pressure,pregnant women with hypertension in pregnancy were divided into mild group and severe group,and related indexes were compared between the groups.The TC,TG,HDL,LDL were divided into four groups according to the interquartile range,and the correlation between the adverse pregnancy outcome and the blood lipid parameters was analyzed,and the differences between the groups were statistically analyzed.Results Abnormal blood lipid levels during pregnancy increased with the increase in blood pressure.Analysis of related factors found that TG(OR=1.368,95%CI: 1.253-1.535,P< 0.05)was an independent positive correlation factor for HDP,TC(OR=2.231,95%CI: 1.384-3.598,P < 0.05)TG(OR=1.673,95%CI:1.207-2.320,P < 0.05)is an independent predictor of severe HDP.Analysis of blood lipid parameters and pregnancy outcomes found that cesarean section was significantly correlated with TG,and neonatal asphyxia,premature delivery and low birth weight infants were significantly correlated with TC,P<0.05.Conclusion 1.The age of pregnant women,body mass index before pregnancy,weight gain during pregnancy may affect blood pressure and blood lipids in patients with hypertension during pregnancy to a certain extent.2.Patients in the severe group have more significant dyslipidemia during pregnancy,and the prevalence of pregnancy complications is also higher.3.Abnormal blood lipids during pregnancy are correlated with adverse pregnancy outcomes,and are positively correlated.4.Pregnancy blood lipids may affect the increase in blood pressure during pregnancy in the early pregnancy,leading to the occurrence of adverse pregnancy outcomes,but in the later period,blood pressure and height may be the main factor leading to adverse pregnancy outcomes.