Clinical Study On The Treatment Of Insomnia Caused By Liver And Spleen Disorder By Chaihu And Longgumuli Decoction Combined With Gaozheng Wuyou San

Objective: This study used Chaihu and Longgumuli Decoction combined with Gaozhen Wuyou San to compare with the Chinese patent medicine Tianmeng Capsule to observe the clinical efficacy of treating liver and spleen disorders insomnia,and provide reference for further clinical application.Methods:Seventy cases of patients with chronic insomnia and liver and spleen disorders in TCM insomnia that meet the 2017 revised "Guidelines for the Diagnosis and Treatment of Insomnia for Adults in China" were included in the study.They were divided into treatment group and control group according to the random number table method,each group 35 cases,the treatment group used Chaihu and Longgumuli Decoction combined with Gaozhen Wuyou San.Take one dose a day,take 200 ml with hot water,and divide it into the morning and evening.Control group medication:Tianmeng capsules,3 capsules each time,divided into morning and evening.Two weeks is a course of treatment,with 2 courses of treatment.The Pittsburgh sleep quality index scale,self-assessment of sleep status and TCM syndrome scores before and after treatment with Chaihu and Longgumuli Decoction combined with Gaozhen Wuyou San in patients with liver and spleen disorders insomnia were observed and analyzed,and the two groups were compared for treatment of liver and spleen The clinical effect of disordered insomnia..Follow-up for 3 months after the end of treatment to evaluate the long-term efficacy of the two groups of drugs.Results:1.The treatment group and the control group were compared on gender,age,and disease course before treatment,and the results were all P>0.05,the difference was not statistically significant,indicating that the two groups of patients were comparable before treatment.2.After statistical analysis,the total effective rate of the experimental results in the treatment group of Chaihu plus Longgumuli Decoction and Gaozhen Wuyou San was91.43%.The total effective rate of the experimental results of Tianmeng Capsules in the control group was 71.43%.The comprehensive curative effect was tested by χ~2test,P=0.031<0.05,the difference was statistically significant,indicating that the curative effect of the Chaihu plus Longgumuli Decoction and Gaozhen Wuyou San group was significantly better than that of the Tianmeng Capsule group after treatment.3.After treatment,the total scores of the Pittsburgh sleep quality index,sleep self-assessment table,and TCM syndrome score table in the treatment group were lower than those in the control group(P<0.05),the difference was statistically significant,indicating that the combination of Chaihu and Longgumuli Decoction combined with peace of mind Powder to treat liver and spleen disorders insomnia can improve sleep better.4.Three months after stopping the drug,the recurrence rates of the treatment group and the control group were 14.30% and 40.0%,respectively,and the difference between the two groups was statistically significant(P﹤0.05).Conclusion: Chaihu and Longgumuli Decoction combined with Gaozhen Wuyou San have the effects of reconciling the liver and spleen,relieving depression and soothing the nerves.It is better than Tianmeng Capsule in the treatment of liver and spleen disorders insomnia,and significantly improves the patient’s sleep status and liver and spleen disorders symptom。...