The Study On The Correlation Between The Distribution Of Female OAB Syndrome And Common Clinical Risk Factors

Objective:This study collected clinical data of female patients with overactive bladder(OAB)from Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine,and statistically analyzed their general data,common clinical risk factors,severity of overactive bladder,and the four-diagnosis data of traditional Chinese medicine.Summarize the correlation between OAB severity and common clinical risk factors and the characteristics of OAB TCM syndrome distribution,and provide a basis for TCM treatment of OAB.Methods:The cases in this study were all OAB patients who were admitted to the Department of Urology,Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine from January 2020 to January 2021.Through the clinical investigation,the general information,clinical common risk factors and four TCM diagnosis data of 185 patients were collected,and the symptom evaluation form of bladder hyperactivity syndrome was completed.The clinical data were summarized into Excel 2016 and statistically analyzed by SPSS 25.0.According to the statistical results,the correlation between the severity of OAB and common clinical risk factors and the characteristics of the distribution of TCM syndromes of OAB were analyzed,and the conclusion was drawn.Results:1.For the patients in this investigation,the youngest is 18 years old,the oldest is 67 years old,and the average age is 43.3 years old.Among them,the 48-57 age group has a higher proportion,accounting for 35.1%.The two age groups,28-37 years old and 58-67 years old,accounted for less than 11.9% and 11.4% respectively.2.The severity of the patients in this survey was mostly mild,accounting for 60.5%,the median age was(28,45,79)years,and the median disease duration was(5,6,6)months;moderately accounted for 35.7 %,the median age is(42.75,48.5,50.25)years,the median duration of the disease is(5,6,8)months;the severity is 3.8%,the average age is47.57±9.59 years,and the duration is the average 16.57±8.16 months.The severity of OAB was positively correlated with age and course of disease(rs=0.208 P=0.004 < 0.05,rs=0.165 P=0.025<0.05).3.The severity of OAB is different in patients with different menstrual status,combined with other system diseases,different pelvic surgery history,different fertility status,and different marital status(P<0.05);delivery complications,treatment status,eating habits,including drinking strong tea Drinks such as,coffee,soda and other spicy foods and different levels of education have no effect on the severity of OAB(P >0.05)4.TCM symptoms that occur> 30% include frequent urination,excessive nocturia,breast lumps,sighs,lower abdomen pain,insomnia,dizziness,perineal pain,breast pain,burning urination,lazy talk,dry mouth,dark menstruation,Swelling,thin white coating,yellow tongue coating,greasy tongue coating,red tongue,stringy pulse,pale tongue,slippery pulse.5.The disease location and syndrome elements involved in OAB patients include heart,spleen,liver,kidney,intestine,and bladder.The disease syndrome elements are Qi deficiency,Yin deficiency,Yang deficiency,blood deficiency,body fluid deficiency,qi stagnation,blood stasis,and cold,dampness,heat,sputum.6.The TCM syndromes of OAB patients can be summarized into 4 syndromes: liver and kidney yin deficiency,deficiency of spleen and kidney,qi stagnation and blood stasis,and accumulation of damp-heat.The distribution of each syndrome is: deficiency of spleen and kidney> accumulation of damp-heat> qi stagnation and blood stasis> deficiency of liver and kidney yin.Among them,there are 93 cases of asthenia syndrome,accounting for50.3%;92 cases of sthenia syndrome,accounting for 49.7%.7.Patients with damp-heat accumulation are younger than those with spleen and kidney deficiency,qi stagnation and blood stasis,and liver and kidney deficiency(P<0.05).Patients with spleen and kidney deficiency are younger than those with liver and kidney yin deficiency(P<0.05).Patients with deficiency syndrome are older than those with positive syndrome(P<0.05),there is no significant difference in the course of patients with different syndromes(P>0.05),and there is no difference in the course of patients with deficiency syndrome(P>0.05).There was no difference in the severity of OAB in patients with different syndromes(P>0.05),and there was no difference in the severity of OAB in patients with deficiencies(P>0.05).Conclusion:The severity of OAB increases with age and the course of the disease.Among them,the severity of OAB is related to marital status,reproductive history,menopause,and other system diseases;the relationship between education level,childbirth complications,history of pelvic surgery,eating habits and severity of OAB needs to be further research.The disease location and syndrome elements involved in OAB include heart,spleen,liver,kidney,large intestine,and bladder.The disease syndrome elements are qi deficiency,yin deficiency,yang deficiency,blood deficiency,body fluid,qi stagnation,blood stasis,cold,dampness,Heat,phlegm.The TCM syndromes of OAB are mainly divided into liver and kidney yin deficiency,spleen and kidney deficiency,qi stagnation and blood stasis,and damp-heat accumulation.The distribution of each syndrome is as follows: spleen and kidney deficiency> damp-heat accumulation> qi stagnation and blood stasis> liver Kidney Yin deficiency.There were 93 cases of deficiency syndromes including spleen and kidney deficiency and liver and kidney yin deficiency,accounting for 50.3%;and the sthenia syndrome including damp-heat accumulation and qi stagnation and blood stasis in 92 cases,accounting for 49.7%.Patients with damp-heat accumulation are younger than other syndromes,and patients with sthenia syndrome are older than those with asthenia syndrome.There is no difference in the severity and course of OAB in patients with different syndromes,and there is no difference in the severity and course of OAB in patients with asthenia and sthenia syndrome.