| Objective: By observing the clinical efficacy of taking traditional Chinese medicine granule Huoxuetongluo Decoction combined with celecoxib in the treatment of cervical spondylotic radiculopathy with qi stagnation and blood stasis,to explore its effectiveness in treating cervical spondylotic radiculopathy with qi stagnation and blood stasis.Methods: From January 2020 to January 2021,90 cases of cervical spondylosis with radiculopathy who met the standard were selected in the Department of Orthopedics and Traumatology of the First Affiliated Hospital of Anhui University of Traditional Chinese Medicin.They were randomly divided into control group I,control group Ⅱ and observation group,30 cases in each group,before treatment The age,gender,course of disease,TCM syndrome score,VAS pain score,NDI index,and cervical spine range of motion of the three groups of patients were analyzed in turn to eliminate differences.The control group Ⅰ took celecoxib capsules orally,twice a day,one capsule at a time,for 14 consecutive days,and the control group Ⅱ took traditional Chinese medicine granules Huoxue Tongluo Decoction orally,once a day,divided into morning and evening for 14 consecutive days.The observation group took Celecoxib capsules and Chinese medicine granules Huoxuetongluo Decoction orally at the same time,the usage and dosage were the same as above,and the treatment was continuous for 14 days.The overall clinical efficacy and clinical observation indicators of the three groups of patients were statistically analyzed and processed before treatment,after treatment and 1 month after the end of treatment,and the differences between the three groups were compared.Results:1.There were no significant differences in the age,gender,and course of the disease among the three groups before treatment(P>0.05),and they were comparable;2.Overall curative effect evaluation: At the end of treatment: the overall effective rate of control group Ⅰ is 76.7%,the overall effective rate of control group Ⅱ is 80.0%,and the overall effective rate of observation group is 90.0%.The non-parametric test of the overall curative effect of the three groups of patients showed that p=0.032<0.05 was statistically different.The difference between the three groups of patients is obvious after treatment,and the observation group is significantly better than the control group Ⅰ and the control group Ⅱ(P<0.05);at 1 month after the end of treatment:the overall effective rate of the control group Ⅰ is 80.0%,the overall effective rate of the control group Ⅱ was 83.3%;the overall effective rate of the observation group was93.3%.The non-parametric test of the overall curative effect of the three groups of patients showed that p=0.012<0.05 was statistically different.The difference was significant at 1 month after the end of treatment.The curative effect of group is obviously better than that of control group Ⅰ and control group Ⅱ(P<0.05);3.Comparison of TCM syndrome scores: There was no statistically significant difference in TCM syndrome scores between the three groups of patients before treatment(P>0.05),and they were comparable;after treatment and 1 month after the end of treatment,the TCM syndrome scores of the three groups were all lower than before treatment,the difference was statistically significant(P<0.05),and the scores of TCM syndromes in the observation group were lower than those of the control group Ⅰ and the control group Ⅱ were statistically significant(P<0.05);4.Comparison of VAS scores: The VAS scores of the three groups of patients before treatment were not statistically significant(P>0.05),and they were comparable;after the treatment and at 1 month after the end of treatment,the VAS scores of the three groups of patients were lower than before treatment,and there were differences Statistically significant(P<0.05),and the VAS scores of the observation group were lower than those of the control group Ⅰ and control group Ⅱ,the difference was statistically significant(P<0.05);5.Comparison of NDI index: There was no significant difference in NDI index of the three groups before treatment(P>0.05),which was comparable;after the treatment and at 1 month after the end of treatmenth,the NDI index of the three groups was lower than before treatment(P<0.05),and the NDI index of the observation group was lower than that of the control group Ⅰ and control group Ⅱ(P<0.05);6.Comparison of cervical spine mobility: the three groups of patients had no statistically significant difference in cervical spine mobility before treatment(P>0.05),and they were comparable;after treatment and at 1 month after the end of treatment,the cervical spine mobility of the three groups was higher than before treatment,The difference was statistically significant(P<0.05),and the cervical spine mobility of the observation group was higher than that of the control group Ⅰ and control group Ⅱ,and the difference was statistically significant(P<0.05);7.Adverse reactions: The blood routine,biochemical and other laboratory indicators of the three groups of patients before treatment,after treatment,and 1 month after the end of treatment were compared.The results showed no significant changes.During the medication,there were no adverse reactions such as allergies and gastrointestinal reactions.Conclusion:Chinese medicine granules Huoxue Tongluo Decoction and Celecoxib capsules can treat cervical spondylotic radiculopathy with qi stagnation and blood stasis.The combination of the two can improve the overall clinical curative effect of patients,cervical spine mobility,and reduce the TCM syndrome score,VAS score and NDI index,it has more significant effects and safety and is worthy of clinical promotion. |
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