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Development of imaging system for scintigraphic analysis of biomaterials

Posted on:2003-04-17Degree:M.SType:Thesis
University:The University of Texas at ArlingtonCandidate:Nadkar, Aalok ArvindFull Text:PDF
GTID:2468390011480485Subject:Health Sciences
Abstract/Summary:
There has been an effort by researchers around the world recently to upgrade analog or semi-digital gamma cameras with newer, faster computer systems. At UT Southwestern, the need for an improved image acquisition and analysis system that is user friendly, and incorporates most of the common features of modern systems prompted the use of LabVIEW for the development of an image acquisition and analysis system. The interface involves a GE 400T nuclear gamma camera connected to a PC with modern operating systems. One of the applications envisioned for this system is imaging the blood-biomaterial response using different radioactive labels for the blood components.; Tests with point sources of radioisotopes have shown that the system is able to acquire single channel and dual channel static planar images. The analysis includes multiple regions of interest selection and calculation of unbiased activities of two isotopes. Time proportionality studies have demonstrated this system is able to quantify the contributions of individual isotopes in a dual isotope acquisition study with point sources of 99mTc and 67Ga. In addition, the system is able to image high contrast regions, and has shown linearity in response to isotope activity.
Keywords/Search Tags:System
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