Changes Of TCM Syndrome Factors Before And After Esophageal Cancer Surgery

ObjectiveUnder the guidance of TCM theory,extract TCM syndrome by observing the changes of clinical symptoms and signs of patients with esophageal cancer before and after operation.Explore the distribution and evolution of TCM syndromes in patients with esophageal cancer,provide an objective basis for the treatment plan in the process of syndrome differentiation and treatment of esophageal cancer,and better utilize the advantages of traditional Chinese medicine in the treatment of esophageal cancer.MethodsSelect patients with esophageal cancer that meet the inclusion criteria,use prospective research methods,collect TCM syndrome information on the 3rd and 7th day before surgery,establish a database using excel form,and use SPSS20.0 software for statistical analysis.The statistical method of syndromes extracts the corresponding syndromes of traditional Chinese medicine,summarizes the changes of syndromes before and after esophageal cancer surgery,and screens out the changes of syndromes with statistical and clinical significance.Results(1)A total of 108 patients with esophageal cancer were included in this study,including 89 males(82.41%)and 19 females(17.59%);the average age was 61.38± 8.71 years,and the majority of patients were over 50 years old.The pathological stages are mainly stage ? and? patients.(2)The most frequent symptoms before surgery are eating choking(71.30%),vomiting and salivation(71.30%),chest pain(63.89%),followed by hiccups(58.33%),acid reflux(56.48%),night sweats(50.00%),Weight loss(47.22%).Before surgery,pale tongue,dark purple tongue,and red tongue appeared more frequently,accounting for 36.11%,32.41%,and 31.48%,respectively.The pulse was mostly pulse slip(30.46%),followed by pulse string(25.86%)and pulse fineness(21.84).%).The prevalence of pathogenic syndromes before surgery was stagnation,blood stasis,phlegm turbidity,and Qi deficiency,which accounted for 38.89%,32.41%,29.63%,and 18.52%,respectively.They were 57.41%,54.63%,and 50.00%,respectively.(3)Symptoms such as choking,vomiting,spitting,hiccups,and acid reflux decreased after the operation,and the symptoms of fatigue(67.60%),shortness of breath(64.81%),pale complexion(27.78%),and loose stools(32.41%)There was a significant increase before,with an increase of 32.41%,32.40%,13.89%,and 20.37,respectively.After the operation,the tongue was light(68.52%)and thin white fur(42.59%),which was higher than that before the operation.The pulse with the highest frequency after operation was pulse fineness(36.07%),an increase of 14.23%compared with that before operation,and pulse slip and pulse string decreased compared with that before operation.The syndromes of qi deficiency and blood deficiency were significantly increased after the operation,with an increase of 37.96%and 13.89%,respectively.The syndromes of qi stagnation,blood stasis and phlegm were decreased.The spleen of spleen syndrome after surgery had the highest frequency,accounting for 85.19%,a significant increase of 35.19%compared with preoperative,and the kidney of spleen syndrome also increased compared with before surgery,an increase of 18.52%.There were statistical differences in the distribution of symptoms,tongue,pulse and syndrome before and after surgery(P<0.05).ConclusionThe results show that the changes of syndromes before and after surgery in patients with esophageal cancer have a certain pattern.The disease syndromes before surgery are mainly stomach,spleen and liver,and the disease syndromes are solid syndromes such as stagnation,blood stasis and phlegm Deficiency syndromes such as Qi deficiency and Yin deficiency also account for a certain proportion,suggesting that pre-operative esophageal cancer treatment should be based on the principles of removing evils,promoting blood circulation,removing blood stasis,strengthening the spleen and removing phlegm,etc.,Nourishing yin and moisturizing,etc.After surgical treatment,the syndrome of spleen in the disease position increased significantly,the qi stagnation,phlegm,and blood stasis of the pathogenic syndrome decreased significantly compared with that before surgery,and the syndrome of qi deficiency and blood deficiency increased significantly compared with that before surgery.At the same time,qi and blood are damaged,so the symptoms of qi deficiency and blood deficiency are mainly after the operation.Although the sputum turbidity,blood stasis and other positive syndromes decreased after the operation,they were not completely removed.therefore.At the same time,the traditional Chinese medicine treatment of esophageal cancer after surgery in the clinic takes JianPi Yiqi Yangxue as the main treatment,and should pay attention to promoting blood circulation and removing blood stasis,and regulating qi and phlegm.