Based On Data Mining Technology, Explore The Medication Rules Of Professor Ling Xiangli In The Treatment Of Common Encephalopathy

Objective:It analyzes the application of modern data mining technology and summarizes the law of drug use of Professor Xiangli Lin’s treatment of the three encephalopathy of insomnia,vertigo,headache,which also has the newcomposition and academic ideas.Methods:Collecting and sorting out the related diagnosis and treatment information about insomnia,vertigo and headache in the original medical record of the old Chinese medicine,it is put into the version of "V 2.5"version of traditional Chinese medicine.It was conducted to sum up the main points of academic ideas that using frequency analysis,association rules,and cluster ana lysis methods to conduct data mining on medical records,which the results of data mining were used to study the law of Professor Xiangli Ling in the treatment of the above diseases.Results:Part 1 Analyse professor Ling Xiangli’s medicine rule of insomnia based on Chinese Medicine Inheritance support systerm.Frequency statistics and assocation rule showed that durgs which Professor Ling used to treatinsomnia are the follows:spine date seed,Caulis Polygoni Multiflori,polygala,curcuma longa,angelica sinensis,peony root,cyperus rotundus I,seed of oriental arborvitae,fried atractylodes,asparagus cochinchinensis,ophiopogon japonicus,radix rehmanniae,poria cocos,bitter orange etc.These durgs mainly to hyperactivity nourishing heart to calm mind,relieving the depressed liver,strengthening spleen and enriching blood,nourishing Yin and clearing the heat.A ssociation rules with the support of a number 33 conditions,durg combination frequency table in the combined rangking:spine date seed,polygala;angelica Sinensis,polygala;polygala,Caulis Polygoni Multiflori;spine date seed,caulis polygoni multiflori;angelica sinensis,spine date seed;curcuma longa,cyperus rotundus 1;angelica sinensis,spine date seed,polygala;seed of oriental arborvitae,spine date seed;seed of oriental arborvitae,peony root;peony root,polygala etc.confidence≥0.8,drug combinations of association rules discovery asparagus cochinchinensis,angelica sinensis,polygala and spine date seed always usage compatibility in the case of 90%.spine date seed as a core durg,it can be used with Ophiopogon Japonicus or angelica sinensis or polygala in most instances.Cyperus rotundus 1 and curcuma longa always usage compatibility,regularly adding peony root or angelica sinensis.Based on hierarchical clustering got 12 new prescriptions for treating insomnia.As follow:radix auckladiae,lanceolata,curcuma longa,cyperus rotundus l;peony root,bitter or ange,ligusticum chuanxiong hort,angelica sinensis,mint;fried malt,amomum,Fried rice sprouts,hawthorn;Ophiopogon Japonicus,radix rehmanniae,fried atractylodes,salvia;hawthorn,mulberry,bitter orange,woodwardia japonica,folium pyrrosiae;catnip,tribulus terrestrisl,periostracum cicadae,dark plum;amomum,semen coicis,preparedpinellia tuber,almond,cardamon;fried rice sprouts,schisandra chinensis,parched hyacinth bean,anemarrhena,glycyrrhiza;Hedyotis diffusa Willd,morinda of ficinalis,plantain,sweetflag,woodwardia japonica;ligusticum chuanxiong hort,dodde r,wolfberry fruit,pericarpium citri reticulatae viride,buddleia officinalis;polygala,cortex moutan,comus,rhizoma alismatis;angelica sinensis,cortex lycii radicis,rhizo ma alismatis,yam.Part 2 Analyse professor Ling Xiangli ’s medicine rule of vertigo based on Chinese Medicine Inheritance support systerm Frequency statistics and assocation rule showed that durgs which Professor Ling used to treat vertigo are the follows:fried atractylodes,salvia,ligusticum chuanxiong hort,curcuma long a,yam,angelica sinensis,cyperus rotundus l,poria cocos,peony root,rhizoma alismat is,Eucommia,astragalus,Caulis Polygoni Multiflori,uncaria,glycyrrhiza,cortex mouta n,radix rehmanniae,achyranthes root,fructus viticis,bitter orange.These durgs main 1y to relieving the depressed liver,activating blood and melting dampness,reinfor cing spleen and kidney.Association rules with the support of a number 15 cond itions,durgcombination frequency greater than 30:fried atractylodes,angelica sinen sis;curcuma longa,cyperus rotundus l;ligusticum chuanxiong hort,fried atractylode s;curcuma longa,fried atractylodes;ligusticum chuanxiong hort,salvia;salvia,fried atractylodes;angelica sinensis,peony root;poria cocos,rhizoma alismatis;fried at ractylodes,cyperus rotundus 1;salvia,yam.confidence≥0.9,drug combinations of association rules discovery cortex moutan with poria cocos or rhizoma alismatis always usage compatibility,in most of the cases they are used at the same time.cortex moutan,rhizoma alismatis and poria cocos could be a group,it can be used in conjunction with radix rehmanniae,or yam,or salvia in the case of 90%.Based on hierarchical clustering got 14 new prescriptions for treating vertigo.As follow:bamboo shavings,semen coicis,prepared pinellia tuber,etrog,radix glehniae;Pericarpium trichosanthis,radix scrophulariae,atractylodes,rose;teasel root,dodder,woodwardia japonica,rhizoma phragmitis,Akebia quinata Decne;peony root,angelica sinensis,poria cocos,radix rehmanniae,cornus,rhizoma alismatis,yam;Cassia occidentalis,uncaria,plantain,Caulis Polygoni Multiflori,Abalone Shell,loran thus parasiticus,leonurus japonicus;almond,catnip,loquat leaf,perilla seed;almond,Common Hogfennel Root,loquat leaf,perilla seed;cimicifuga foetida,bupleurum,yam,lanceolata,tangerine peel;rhizoma corydalis,radix scrophulariae,rose,cassia twig,atractylodes;polygala,Caulis Polygoni Multiflori,Albizzia julibrissin,uncaria,loranthus parasiticus,leonurus japonicus,eucommia;lophatherum gracile,spine date seed,salvia,Akebia quinata Decne;fried malt,artemisia capillaris,fried rice sprouts,loosestrife,magnolia officinalis,Pericarpium trichosanthis;prepared radix rehmanniae,rhizoma alismatis,yam,poria cocos,radix rehmanniae,cortex lycii radicis;loranthus parasiticus,leonurus japonicus,achyranthes root,Eucommia,uncaria,Caulis Polygoni Multiflori,Abalone Shell,Tall Gaxtraodia Tuber.Part 3 Analyse professor Ling Xiangli ’s medicine rule of headache based on Chinese Medicine Inheritance support systerm Frequency statistics and assocation rule showed that durgs which Professor Ling used to treat headache are the follows:peony root,cyperus rotundus 1,ligusticum chuanxiong hort,curcuma longa,fructus viticis,angelica sinensis,scutellaria,fried atractylodes,Caulis Polygoni Multiflori,glycyrrhiza,spine date seed,uncaria,leonurus japonicus,Eucommia,fried malt,astragalus,prepared radix rehmanniae,rhizoma corydalis,lanceolata,loranthus parasiticus.These durgs mainly to relieving liver qi stagnation,strengthening spleen and replenishing qi,activating blood analgesia,nourishing liver and kidney.Association rules with the support of a number 17 conditions,durg combination frequency table in the combined rangking:curcum a longa,cyperus rotundus 1;ligusticum chuanxiong hort,peony root;curcuma longa,peony root;ligusticum chuanxiong hort,fructus viticis;peony root,cyperus rotundus 1;peony root,fructus viticis;fried atractylodes,peony root;angelica sinensis,peony root;ligusticum chuanxiong hort,angelica sinensis;ligusticum chuanxiong hort,curcuma longa etc.confidence≥0.9,drug combinations of association rules discovery leonurus japonicus,Caulis Polygoni Multiflori and uncaria always usage compatibility in the same time,At the same time,it is often compatible with eucommia.peony root usually combined with rhizoma corydalis or ligusticum chuanxiong hort,fried atractylodes.Fructus viticis,cyperus rotundus 1 and curcuma longa always together in the case of 90%.Based on hierarchical clustering got 8 new prescriptions for treating vertigo,As follow:schisandra chinensis,polygala,radix sileris,seed of oriental arborvitae,Ophiopogon Japonicus;Tall Gaxtraodia Tuber,scutellaria,loranthus parasiticus,angelica sinensis;fructus viticis,ligusticum chuanxiong hort,achyranthes root,prepared radix rehmanniae;salvia,prepared pinellia tuber,cortex lycii radicis,curcuma longa;catnip,mint,balloonflower,great burdock achene;poria cocos,lanceolata,tangerine peel,cimicifuga foetida;radix rehmanniae,magnolia officinalis,mulberry,hawthorn;leonurus japonicus,eucommia,Caulis Polygoni Multiflori,uncaria,fried atractylodes.Conclusion:Based on the auxiliary platform of traditional Chinese medicine,Professor Xiangli Ling’s medicine for treating common encephalopathy was analyzed by modern data mining.It was found that Professor Xiangli Ling’s first defense is true and false when treating brain disease,seizing the key pathogenesis,making good use of methods,striving to balance,not forgetting to adjust emotions,paying attention to modern pharmacology research,and integrating Chinese and Western medicine.It brings to bear modern mining techniques that is more effective to excavate and analyze the academic thoughts and clinical experiences of famous Chinese medicine practitioners.At the same time,the thought and clinical experience of modern famous Chinese medicine practitioners have important sense to our present medicine.