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The Morphological Changes Of Soft Tissues Under The Knee Musculature Lesions Of KOA Patients Were Observed By MRI

Posted on:2020-11-29Degree:MasterType:Thesis
Country:ChinaCandidate:X WeiFull Text:PDF
GTID:2434330599977000Subject:Acupuncture and massage
Abstract/Summary:PDF Full Text Request
Objective: In this study,MRI was used as the main research method to observe the morphological changes of the knee joint lesions in KOA patients,and further deepen the research on the scientific mechanism of the tendons.Material and method:The total number of patients with knee osteoarthritis(KOA)ranged from 2018.3 to 2019.3 in the first and second hospitals affiliated to Liaoning University of Traditional Chinese Medicine.The patients were screened for the criteria by diagnostic criteria,inclusion criteria,exclusion criteria,and rejection criteria,and there was no significant difference in gender,age,weight,and general living conditions.Patients who met the inclusion criteria entered the study in order and voluntarily signed informed consent.The 20 KOA patients were lying flat on their backs,keeping the environment quiet and the light and temperature stable.After breathing and feeling calm,palpation is performed in turn according to the prescribed examination order for Cheng Yuci,Yuci,Yuzhongxia,and Shiyang.Twenty patients were then examined using the Siemens ESSENZA 1.5T NMR instrument.The coronal,transverse and sagittal positions of the four lesions—Chengdu,Yuci,Qiongxia and Shiyangyang were scanned,and T1 WI weighting,T2 WI weighting and proton density weighting were performed..The scanning layer thickness of the nuclear magnetic resonance apparatus was set to 4 mm,the layer spacing was set to 1 mm,the FOV was set to 18 cm x 18 cm,and the number of excitations was set to 2.At the time of the examination,the medical staff will ask the patient to keep the knees straight.Observation indicators:1 Observing the morphological changes in the MRI images of the knee joints at the same location in the selected four sites;2 For the selected lesions of the tendons,perform image analysis to determine what type of lesions are different,and whether there is similarity between them.Results:1.According to the MRI image obtained from the experiment,and through image processing,the original data required for the experiment are obtained.2.after data sorting,through group t test and rank sum test,except that the thickness at the origin of popliteal tendon was not significantly different from that of the healthy group,the other three groups were all p < 0.05,with statistical significance.3.According to the contrast analysis of nuclear magnetic resonance imaging between KOA patients and healthy people,it is found that KOA patients often have pathological abnormal changes of soft tissue,such as synovial edema,hyperplasia,joint cavity effusion,ligament calcification,etc.4.The next pain nodule and tendon nodule in patella have certain difference in MRI images.Conclusion:1.Compared with MRI images of healthy volunteers,the ligament thickness of KOA patients at the patellar tibialis ligament starting point,the transverse ligament starting point and the patellar ligament starting point,which are several common KOA patients,shows a significant thickening trend.2.Compared with MRI image data of healthy volunteers,KOA patients mostly have pathological changes of synovium,such as increased synovium volume,obvious hyperplasia of synovium,formation of a large number of villi or nodules,and signs of effusion in joint cavity.3.Taking the focal point of the next intrapatellar tendon junction as an example,according to the MRI image data of the patients in the experimental group,the observed patellar tibialis ligament showed a thickening trend in all six patients,but the thickening trend was more obvious in patients with tendon nodules than in patients with painful nodules.4.Nuclear magnetic resonance imaging studies of 4.KOA patients show that there may be abnormal changes of thickening of ligaments in common clinical nodulepoints.Nuclear magnetic resonance technology is helpful to establish an objective diagnosis and evaluation system for knee osteoarthritis.5.Painful nodule and tendon nodule may be different pathological manifestations caused by different stages of development of nodule.
Keywords/Search Tags:Meridian, Knee Osteoarthritis, Tendon, Tendon Lesion, MRI, Morphological Changes
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