Clinical Impacts Of Different Electroacupuncture Treatment Frequencies On Female Overactive Bladder

Objective: This clinical research is a randomized and controlled trial,to objectively evaluate the clinical impacts of different electroacupuncture(EA)treatment frequencies on female overactive bladder(OAB),taking urinary symptom score and quality of life of the patient as an evaluation method.So that we can select a better EA treatment frequency for female diagnosed with OAB.Method: Eighty-three female patients with OAB were randomly divided into three groups: once a week group(n = 27),twice a week group(n = 28)and three times a week group(n = 28),short for once group,twice group and three times group in the following statement.The following main acupoints were selected: Guanyuan(RN4),Zhongji(RN3),Dahe(KI12),Shuidao(ST28),Sanyinjiao(SP6).All patients were treated with EA.Zhongji and left Dahe,Guanyuan and right Dahe were separately connected with EA.30 Hz continuous wave was set on the EA machine.The patients divided into once group was treated once a week.The patients in the twice group were treated twice a week.And the patients in the three times group were treated three times a week.Female OAB patients were treated for 20 minutes each time.And the study lasted for 4 weeks.The Overactive Bladder Syndrome Score(OABSS)and urinary symptom score(International Prostate Syndrome Score,I-PSS)and Quality of Life score(Qo L)were assessed before treatment,1-week treatment,2-week treatment,3-week treatment and after 4-week treatment respectively.Results:Comparison within groups:(1)The total score of OABSS: The total score of OABSS in the once group began to decline after 2-week treatment(P<0.05),except that there was no significant change between 3-week and 4-week treatment.The total score of OABSS in twice and three times group both showed a downward trend after 1-week treatment(P<0.05).(2)The total score of I-PSS: The total score of I-PSS in the once group began to decline after 2-week treatment(P<0.05),except that there was no significant change between 2-week and 3-week treatment.The total score of I-PSS in the twice group began to decline after 2-week treatment(P<0.05).The total score of IPSS in the three times group began to decline after 1-week treatment(P<0.05).(3)Frequent urination: There was no significant difference of frequent urination score at different time points in the once group(P>0.05).The score of frequent urination in twice group and three times group began to decline after 2-week treatment(P<0.05),except that there was no significant change between 2-week and 3-week treatment.(4)Nocturia: The nocturia score of the once group began to decline after 2-week treatment(P<0.05),except that there was no significant change between 3-week and 4-week treatment.The nocturia urine score in the twice group began to decline after 2-week treatment(P<0.05),but did not change after 2-week and 3-week treatment.The nocturia score of three times group began to decline after 1-week treatment(P<0.05),except that there was no significant change between 1-week and 2-week treatment.(5)Urinary urgency: The score of urinary urgency in the once group began to decline after 3-week treatment(P<0.05),except that there was no significant change between 3-week and 4-week treatment.The score of urinary urgency in the twice group began to decline after 2-week treatment(P<0.05),except that there was no significant change between 2-week and 3-week treatment.The urinary urgency score began to decrease continuously in the three times group after 1-week treatment(P<0.05).(6)Urgent urinary incontinence: The score of urgent urinary incontinence began to decrease in the once group 2-week treatment(P<0.05),but did not change at 2-week,3-week and 4-week treatment.The score of urgent urinary incontinence began to decrease continuously in the twice group after 2-week of treatment(P<0.05).The score of urgent urinary incontinence began to decrease in the three times group after 1-week treatment,but did not change at 3-week and 4-week treatment.(7)Vesical tenesmus: There was no significant difference in vesical tenesmus score at different time points in the once group(P>0.05).The vesical tenesmus score began to decrease in the twice group and three times group after 2-week treatment(P<0.05),but did not change after 2-weeks and 3-week treatment.(8)Straining urination: There was no significant difference in straining urination score at different time points in the once group(P>0.05).The score of straining urination began to decrease in the twice group after 3-week treatment(P<0.05),but did not change at 3-week and 4-week treatment.The score of straining urination began to decrease in the three times group after 3-week treatment(P<0.05).(9)Quality of life: The quality of life score of the once group began to decrease continuously after 2-weeks treatment(P<0.05).The score of quality of life began to decrease continuously after 1-weeks treatment in the twice and three times group(P<0.05).Comparison between groups:(1)After 3-week treatment,the total score of OABSS,the score of urgent urinary incontinence in the three times group were significantly lower than those in the once group and the twice group(P<0.05),but there was no significant difference in the total score of OABSS and the score of urgent urinary incontinence between the once group and the twice group(P>0.05).After 4-week treatment,the total score of OABSS,the score of urination urgency and quality of life in the twice group and the three times group were significantly lower than those in the once a week group(P<0.05).There was no significant difference in the total score of OABSS,the score of urination urgency and quality of life between twice group and three times group(P>0.05).After 4-week treatment,there was no significant difference in the total score of I-PSS,the score of frequent urination,nocturia,vesical tenesmus and straining urination in the once group,the twice group and the three times group(P>0.05).(2)After four-week treatment,the total effective rate was 22.22% in the once group,75% in the twice group and 96.43% in the three times group.The curative effect of three times group and twice group was better than that of once group(P<0.05).There was no significant difference of curative effect between the twice group and three times group(P>0.05).Conclusion:(1)After 4-week treatment,EA treatment once a week,twice a week and three times a week could effectively improve the urination symptoms and improve the quality of life of female OAB patients.And the curative effect of EA treatment twice a week was the same as that of three times a week.However,both were better than EA treatment once a week.EA treatment once a week couldn't improve symptoms of frequent urination,vesical tenesmus and straining urination in female OAB patients.(2)The curative time of EA treatment three times a week in improving the symptoms of urinary urgency,nocturia and urgent urinary incontinence was earlier.And the curative time of EA treatment twice a week in improving the symptoms of frequent urination,vesical tenesmus and straining urination was the same as that of EA treatment three times a week.