Male Climacteric Syndrome Observation On The Clinical Effect Of Time-sharing On Yang Deficiency In Spleen And Kidney

Objective To evaluate the efficacy and safety of time-sharing in the treatment of male climacteric syndrome by observing the clinical effect of time-sharing in the treatment of male climacteric syndrome with deficiency of spleen and kidney.Methods 90 cases of male patient who diagnosed as climacteric syndrome and Yang deficiency in spleen and kidney from male outpatient department of Yinchuan Traditional Chinese Medicine Hospital and Yinchuan Hui Nationality Medicine Hospital of Traditional Chinese Medicine affiliated to Ningxia Medical University between July 2018 and August 2019 were chosen to be divided into treatment group ? control group 1 and control group 2 randomly,each group with 30 cases.In the treatment group,30 patients were given warm boiled water and delivered 100 ml of Wenpi decoction after meals at 9am-11 am and Yougui decoction with 100 ml warm boiled water at 17am-19 am.The twelfth meridian is the spleen meridian at the time of spleen(9-11pm),the opening level of the spleen meridian is the most vigorous,so warm boiled water was used to put the Wenpi decoction in order to warm the middle and invigorat the spleen,while in 17 to 19 o 'clock,the opening level of the kidney meridian is the most vigorous,so warm boiled water was used to put the Yougui decoction to nourish the kidney andstrengthen the Yang Qi.Patients in the Control group 1 were given testosterone undecanoate with a starting dose of 120 mg,60mg per time after meals in the morning and evening for 3 weeks.Changing the maintenance dose to 80 mg,40mg each morning and evening with warm boiled water after meals for the remaining 5 weeks,twice a day.Control group 2: the patients were instructed to take Wenpi decoction and Yougui decoction 50 ml together with warm boiled water twice a day each morning and afternoon after meals.Results After treatment,the TT and FT levels increased significantly in the three groups,and SHBG levels decreased after treatment,which were significantly different from those before treatment(P<0.05).There was no significant difference in TT,FT and SHBG between the three groups after treatment(P>0.05).The symptom scores of PADAM in all three groups were significantly lower than those before the treatment(P<0.05).there was no significant difference in the symptom scores of PADAM among the three groups(P>0.05).The scores of TCM syndromes in the three groups were all decreased compared with those before treatment,and there were significant differences compared with those before treatment(P<0.05).There was no significant difference in TCM syndrome scores among the three groups after treatment(P>0.05).Conclusion1.There was no significant difference between the three groups of patients in the improvement of PADAM symptoms and TCM syndrome scores,the changes of serum detection indexes and the comparison of effect were not different.2.Time-sharing therapy can tonify the kidney by warming Yang,tonifying the spleen Yang,tonifying the spleen and kidney meridians,reconciling the nature and the acquired as well as the dynamic balance between Yin and Yang of the human body,so as to regulate the whole of the body.3.Time-sharing treatment for splenic and renal Yang deficiency of male climacteric syndrome has no adverse reaction occurred,and the method is safe.