Relationship Between Sedentary Behavior And Metabolic Syndrome In Middle-aged And Elderly Individuals

Objective To explore the relationship between sedentary behavior and metabolic syndrome(MS)and its diagnostic components in middle-aged and elderly individuals.Methods We used the baseline date from Lanzhou area of “REACTION” Study,and total of 9,518 eligible residents aged 40 to 75 years were selected.we extracted data of questionnaires,physical examinations and laboratory tests we needed.According to 2013 Chinese diabetes society MS diagnostic criteria(CDS 2013)diagnosed the subjects included.We divided the subjects into three groups : ?21.0 h/W,21.0~42.0 h/W and >42.0 h/W according to their total sedentary time,into three groups:<2.0 h/d,2.0~4.0 h/d and ?4.0 h/d according to their TV viewing time,and three groups:<2.0 h/d,2.0~4.0 h/d and ?4.0 h/d according to mentally-active sedentary(using computer,reading books,playing video games)time.Partial correlation analysis was used to analyze the correlation of sedentary time,TV viewing time,mentally-active sedentary time with diagnostic components of MS.Binary logistic regression analysis was used to explore the relationship between total sedentary behavior,TV viewing and mentally-active sedentary behavior and the risk of MS and its diagnostic components respectivly.Results1.The prevalence of MS in the study was 40.9%,it was higher in males(51.2% VS 36.8%),P<0.05.The total sedentary time,TV viewing time and mentally-active sedentary time was(34.1±17.3)h/W,(2.5±1.6)h/d and(1.3±1.7)h/d respectively,and all of them were higher in males.2.Compared with total sedentary time ?21.0 h/W group,the prevalence of MS in the 21.0~42.0 h/W group was higher.As the TV viewing time increased,the prevalence of MS increased.As the mentally-active sedentary time increased,the prevalence of MS decreased(all P<0.05).3.Partial correlation analysis showed that after controlling for confounding factors,the total sedentary time was positively correlated with WC,BMI and TG levels(all P<0.05).The TV viewing time was positively correlated with TG,LDL-C,and TC levels(all P<0.05).The mentally-active sedentary time was negatively correlated with FBG,2hPG,HbA1 c,WC,and SBP levels(all P<0.05),and positively correlated with DBP level(P <0.05).4.Logistic regression analysis showed: After controlling for confounding factors,compared with total sedentary time ?21.0 h/W group,the 21.0~42.0 h/W group and >42.0 h/W group both had an increased risk of MS and central obesity(all P<0.05).In males,the >42.0 h/W group had an increased risk of MS,central obesity and low HDL hyperlipidemia(all P<0.05).In females,the >42.0 h/W group had an increased risk of MS,central obesity and hypertension(all P<0.05).5.Logistic regression analysis showed: After controlling for confounding factors,compared with the TV viewing time <2.0 h/d group,the >4.0 h/d group had an increased risk of MS and hypertriglyceridemia(P<0.05).In males,both the 2.0~4.0 h/d group and ?4.0 h/d group had an increased risk of MS,central obesity and hypertriglyceridemia(all P<0.05).In females,there was no significant correlation between TV viewing time and MS,but the ?4.0 h/d group had an increased risk of hypertension and hypertriglyceridemia(all P<0.05).6.Logistic regression analysis showed: After controlling for confounding factors,compared with the mentally-active sedentary time <2.0 h/d group,both 2.0~4.0 h/d and ?4.0 h/d group had a decreased risk of MS,central obesity and hyperglycemia(all P<0.05).In females,the 2.0~4.0 h/d and ?4.0 h/d group had a decreased risk of MS,central obesity,and hyperglycemia and hypertension(all P<0.05).And the ?4.0 h/d group have a decreased risk of hypertriglyceridemia(P<0.05);In males,there was no significant correlation between mentally-active sedentary time and the risk of MS and its components.Conclusion Total sedentary behavior and TV viewing may be independent risk factors for MS.TV viewing and mentally-active sedentary had distinct associations with MS among middle-aged and elderly individuals.