Based On A Cross-sectional Survey Of Metabolic Syndrome Of Tcm Etiology And Pathogenesis Research

Objective:To analysis and classify the Etiology and Pathogenesis of Traditional Chinese Medicine in Metabolic Syndromes based on cross-sectional study,and provide data support for the prevention and early intervention on the metabolic syndrome.Methods:The study runs on four steps:the expert interview, expert survey, the formulation of the clinic questionnaires of TCM syndromes of MS, the cross-sectional study.The cross-sectional investigation was the main part of the study, conducted in7centers,1684cases of patients with MS as the observation group,and306healthy samples as normal control group.Collect the general information and Chinese medical information, anthropometry, medical history,life habit and detection of clinical lab index,etc.Establish a database,all data need double-check entry,and export data by technicians,use SPSS19.0statistical software for data analysis.The data analysis methods include descriptive statistical analysis(the frequency and constituent ratio analysis). Linear Regression Test,Chi-square analysis. Finally,summarized the pathogenic factors and pathogenesis of MS, puts forward the data support for the early intervention measures of MS.Result:1.General information:a total of1990valid cases, including1684cases of MS group,306cases of normal group. Group MS:1:1.26ratio of men to women. All subjects were aged for52.64±11.38(years old), and the metabolic syndrome were54.71±10.01(years old), can be seen through the analysis of51years to70years the largest number, the total number of68.57%, followed by41years to50years, accounted for23.93%. All the1430patients in the state of being overweight or obese, MS with obese patients accounted for84.92%. and belongs to the abdominal obesity.2.Lifestyle habits:MS group had a sedentary lifestyle habits in71.8%, compared with the normal group, there were significant differences (P<0.01). average sedentary time was2.41±2.83hours/day. Tobacco and alcohol are the influential factors for males.The rate of sedentary lifestyle habits in Liaoning Benxi, Shanxi Lu"an, Shandong Rizhao Huafang area was significantly higher than that in other provinces and cities (P<0.05). Predators in Liaoning and Shandong area was significantly higher than that in other provinces and cities (P<0.05), and the Beijing Area (35.2%) were significantly lower than the average level.The average amount of staple food in group MS is317±146g, most can eat1500g,the amount of staple food in normal group is265±107g (P=0.001<0.05), the main content and weight increasing of food has no significant relationship (P>0.05), but most of them tend to eat meat,68.3%people often eat carnivorous.34.7%of the patients in group MS were often accompanied by abnormal emotion,21.3%of them was irritability,while16.6%was depression or anxiety.3.Medical history in MS group:54.6%of the patients had family history of MS,40.3%of the patients had a history of hypertension,31.6%of the patients with previous history of high blood lipids, diabetes patients account for16.9%. Dyslipidemia accounted for64.1%, hypertension accounted for66.7%,25.2%of them in MS group subjects only one diagnosis, but43.3%of people with2kinds of diagnosis, and31.5%people with3or more than3of the diagnosis, but only0.2%with5diagnosis.4. Using the chi-square test, find the positive rate of extraction above10%(P<0.05) index,and combining with the clinical,finally have extracted54variables5. According to the symptoms analysis, MS basically reflects the characteristics of the pathogenesis of phlegm heat, phlegm, blood stasis, and mainly invovles the spleen and stomach, or affects liver, heart and kidney.Conclusion:This study summarized the TCM etiology and pathogenesis of the metabolic syndrome, which provide data support for medical prevention and early intervention of metabolic syndrome.l.The etiology of MS:the occurrence of MS is related to age, gender, obesity and living habits, and commonly seen among the elderly, and sedentary habits is one of the most important reasons.2.MS has familial aggregation, dyslipidemia and hypertension are the main components. MS often has2or more than2abnormal compositions.3.MS pathogenesis:MS positive by phlegm and heat, deficiency in spleen dampness, phlegm and heat is the main pathological basis of MS.