Review Of Clinical Characteristics Of Autoimmune Pancreatitis

Autoimmune pancreatitis(AIP)is a kind of autoimmune related chronic pancreatitis.AIP is divided into two subtypes: type 1 AIP is called the Lymphoplasmacytic Sclerosing Pancreatitis(LPSP),which is characterized by infiltration of Ig G4 positive cells and high level of serum Ig G4 and considered to be a part of the Ig G4 related disease(Ig G4-RD)in pancreas;Type 2 AIP is called idiopathic duct-centric pancreatitis(IDCP),which has no obvious correlation with Ig G4 and is characterized by granulocytic destruction of the ductal epithelium.Type 2 AIP is regarded as a pancreatic specific disease,and about 30% of type 2 AIP is accompanied with the inflammatory bowel diseases.Because the pathogenesis of AIP is unclear,diagnostic criteria is not uniform and treatment measures are dominated by expert consensus for lacking of high-quality evidence,so this review summarizes the progress of the etiology,diagnosis and treatment of AIP.