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Therapeutic Effect Of Zuo Jin Wan Jiawei(ZJW)in The Treatment Of HP

Posted on:2021-05-28Degree:MasterType:Thesis
Country:ChinaCandidate:Y Q BuFull Text:PDF
GTID:2404330611491849Subject:Internal medicine
Abstract/Summary:PDF Full Text Request
Through formal and reasonable research methods,we explored whether ZJW Joint Standard Triplet has a positive HP eradication effect compared with the currently accepted standard of bismuth in China,and observe the improvement of clinical-related symptoms.Method:A total of 55 patients with dyspeptic symptoms who were HP-positive in the gastroenterology clinic of our hospital from December 2017 to December 2018 were selected.The above patients were randomly divided into two groups.Twenty-eight patients in the treatment group were treated with ZJW,esomeprazole,amoxicillin,and clarithromycin,and 27 patients in the control group were given esomeprazole,amoxicillin,and clarithromycin.Oramycin and bismuth potassium citrate were orally administered.Both regimens were discontinued after 14 days of oral administration and reviewed for 13C or 14C for 1 month.Follow-up records were recorded for post-prandial fullness,early satiety,upper abdominal pain,belching,and nausea.,Antacid heartburn 6 dyspepsia scores and type and severity of adverse reactions.Result:The eradication rate of HP in the treatment group was 85.7%,and the eradication rate of HP in the control group was 77.8%.The eradication rate of the two groups was not statistically significant(P>0.05).The scores before and after treatment in the treatment group were 5.04±3.56,0.86±1.08,and the symptom scores before and after treatment in the control group were 4.11± 2.12,1.7±1.77,and the dyspepsia scores in both groups were improved to some extent.The difference was statistically significant(P<0.05).The improvement rates of the symptom scores of the treatment group and the control group were 82.46±19.92%and 62.67± 35.47%,respectively.The difference was statistically significant(P<0.05).The effective rate of symptom relief in the treatment group was 96.43.%,in the control group was 66.67%,and the difference was statistically significant(P<0.05).The incidence of adverse reactions in the treatment group was 10.7%,and in the control group was 55.5%,which was statistically significant(P<0.05).Conclusion:ZJW combined with Triple root eradication treatment of HP is similar to standard quadruple,and it is better than sputum tetraad in the improvement of dyspepsia,and the incidence of adverse reactions is less,which can improve patient compliance.
Keywords/Search Tags:Zuo Jin Wan jiawei, HP eradication rate, indigestion
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