| Objective:The morbidity of endometriosis has been ascending in recent years.Deep infiltrating endometriosis(DIE)is the most advanced type of endometriosis.The treatments for patients with DIE and fertility desire are controversial.Most scholars believe that laparoscopic surgery is the best option.There is no agreement on whether patients should wait for spontaneous pregnancy or undergo assisted reproductive technology.The purpose of this study was to explore the differences in postoperative pregnant rates among patients with deep infiltrating endometriosis with fertility desire.Materials and Methods:We had search Pubmed,OVID Medline,Cochrane Library,Embase published before 2019-10-31,According to the inclusion criteria and exclusion criteria,a total of 17 articles were selected.A 95%confidence interval(CI)was used for clinical pregnancy data,and a random-effect model was used for meta-analysis.Subgroup analysis and sensitivity analysis were performed using Review manager 5.3.Results:Among patients with fertility desire,370/1142(32.40%)conceived spontaneously after surgery,compared with 306/1108(27.62%)got pregnant after surgery and assisted reproductive technology(P=0.36,I~2=82%).There is no significant statistical significance in this comparison and the heterogeneity is high.Then,we performed subgroup analysis and found that the heterogeneity was not caused by fertility status,surgical methods or study characteristics.Conclusion:Through this meta-analysis,we think that surgery combined ART or not doesn't effect on pregnancy rate in patients with DIE.They can choose to wait for spontaneous pregnancy or an assisted reproductive pregnancy. |
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