Clinical Observation Of Wenjing Tongluo Decoction In The Treatment Of Cold-dampness Obstruction Syndrome Of Knee Osteoarthritis

Research objective:To observe the clinical efficacy of Wenjing Tongluo Decoction in treating knee osteoarthritis of cold dampness and obstruction syndrome.Research methods:In this study,60 patients with knee osteoarthritis who were diagnosed with cold and dampness syndrome were selected from February 2019 to February 2020 in the Orthopaedics Department of Jiangsu Province Traditional Chinese Medicine Hospital.Randomly divided into control group?treatment group A?treatment group B,each 20 cases,the control group used etocoxib,the treatment group A used Wenjing Tongluo Decoction combined with etocoxib,and the treatment group B used Wenjing Tongluo Decoction.This study takes 2 weeks as a course of treatment and 2 consecutive courses of treatment.Pain visual analog scale(VAS score),Western Ontario and Maastricht Osteoarthritis Index Visualization Scale(WOMAC Index)were used as indicators.The three groups were treated before treatment,at the end of 1 course and at the end of 2 courses Patients were scored,and statistical analysis can evaluate scientific curative effects.Research results:1.The basic data of the three groups show no statistically significant difference in gender,age,course of disease,imaging grade,VAS score before treatment,WOMAC total score and WOMAC knee function score(P>0.05).2.After 2 and 4 weeks,VAS score,WOMAC total score and WOMAC knee joint function score of the three groups were obviously improved,comparing with those before treatment(P<0.05).The results showed that the three groups of treatment were effective for koa patients of cold dampness obstruction type.3.After 2 weeks of treatment,statistically significant differences were showed in VAS score,WOMAC total score and WOMAC knee joint function score between the treatment group A and the treatment group B(P<0.05).The differences of treatment group B and the control group in VAS score,WOMAC total score and WOMAC knee joint function score showed no statistical significance(P>0.05).There was no significant difference in VAS score between the treatment group A and the control group(P>0.05),but there were significant differences in total score of WOMAC and knee function score of WOMAC(P<0.05).4.After 4 weeks of treatment,there were significant differences in VAS score,WOMAC total score and WOMAC knee joint function score in three groups(P<0.05).There was no significant difference in VAS score,WOMAC total score and WOMAC knee joint function score between treatment group B and control group(P>0.05).5.After 2 weeks of treatment,the clinical effective rate of the three groups was 0%,there was no statistical difference(P>0.05).After 4 weeks of treatment,there was a significant statistical difference in the clinical effective rate between the three groups(P<0.05).Compared with the two groups,the effective rate of treatment group A was 60%,which was significantly higher than 25%of treatment group B and 20%of control group(P<0.05).The effective rate of treatment group B was slightly higher than control group,but the difference was not statistically significant(P>0.05).Research conclusion:The three groups of methods are all effective in treating knee osteoarthritis of cold dampness and obstruction syndrome,and the effect of using Wenjing Tongluo Decoction alone is similar to that of using etocoxib alone,but the combined effect is more significant.