Clinical Observation Of Professor Li Qiyi In The Treatment Of Hyperhidrosis

Objective:Through the outpatient hyperhidrosis in patients with clinical data were retrospectively analyzed,looking for a risk factor for hyperhidrosis,sum up the clinical features of patients with hyperhidrosis,observe hyperhidrosis of cytokines(IL-6,IL-8,SOD,NO),the influence of search for the diagnosis of hyperhidrosis,assess the biomarker of help,and summarized the professor Li Qiyi khan syndrome patients treatment experience.Methods:Case data of hyperhidrosis patients who visited professor Li Qiyi's clinic on July 1,2018,solstice,2019,November 30,2019 were collected.The gender,age,HDSS score before and after treatment,body mass index,smoking history,drinking history,dietary preference and previous medical history of patients with sweat syndrome were analyzed using Excel.Location of hyperhidrosis,duration of hyperhidrosis,aggravating factors,frequency of hyperhidrosis,hyperhidrosis area,degree of hyperhidrosis,and facultative symptoms;Cytokine test results of patients with sweat syndrome;TCM classification,treatment,adverse reactions were counted.Statistical software SPSS26.0 was used for statistical analysis.Research results:1.The ratio of male to female in 160 patients with hyperhidrosis was 1:1.08,with an average age of 47.36 years.The proportion of patients with severe sweating syndrome from high to low according to body mass index was:normal(51.96%),overweight(29.41%),obese(12.75%),and underweight(5.88%).The patients with non-severe sweating syndrome were normal(41.30%),overweight(32.61%)and obese(26.09%).There was a significant difference in body mass index distribution between the two groups(Z=-2.368,P=0.018<0.05).The proportion of endocrine and metabolic diseases was the highest(26.9%).2.Most of the patients with sweat syndrome were in the upper body(41.9%),followed by the whole body(31.9%),followed by the head(10.6%).The sweating frequency,sweating area and sweating degree of patients with severe sweating syndrome were significantly higher than those without severe sweating syndrome,with statistically significant differences(Z values were-3.22,-3.602,-3.534,respectively.P were 0.001,0.000 and 0.000,respectively).Among the patients with sweat syndrome,76.25%had aggravating factors,among which activity aggravating factors accounted for 65%,eating aggravating factors accounted for 41.9%,high temperature aggravating factors accounted for 37.5%,stress aggravating factors accounted for 33.1%,stress aggravating factors accounted for 1.3%,and cloudy and rainy factors accounted for 0.6%.The proportion of the patients with sweat syndrome was from high to low:splenic symptoms,cardiac symptoms,hepatic symptoms,pulmonary symptoms,and the symptoms of chills were similar to those of heat.3.The highest proportion of abnormal cytokines in patients with sweat syndrome was IL-8(88.52%).The second was IL-6(42.62%),followed by SOD(36.07%).Finally,there was NO,accounting for 26.23%.Among them,there were 27.87%reduction of SOD and 24.59%reduction of NO.Further analysis showed that there was no significant difference in the above indexes between severe and non-severe sweats.4.According to traditional Chinese medicine,the proportions of patients with hyperhidrosis were from high to low,respectively,as follows:spontaneous sweating(78.8%),night sweats(52.5%),and hot sweating(23.1%).Among them,35%of the patients had both spontaneous sweating and night sweating,and 11.25%had both.Professor Li Qiyi's treatment of sweat syndrome has the characteristics of multiple methods,but to the cold mainly.Professor Li believes that sweat syndrome is mainly empirical and closely related to the heart,spleen and stomach.There was a significant difference in the HDSS score of 160 patients with khan syndrome before and after treatment,that is,(Z=-6.607,P=0.000<0.05),and the score after treatment was significantly lower than that before treatment.During the course of treatment,8 patients(5%)developed adverse reactions to the digestive system.Conclusion:In this study,There are more overweight and obese patients with sweat syndrome.The abnormal expression of cytokines(IL-6,IL-8,SOD,NO)in patients with sweat syndrome remains to be further studied.Professor Li Qiyi has a definite therapeutic effect on hyperhidrosis syndrome,which is worth further study and exploration.