Hypernatremia And Disease Outcome In Patients With Severe Head Injury

OBJECTIVE: To retrospectively analyze the relationship between hypernatremia and disease outcome in patients with severe traumatic brain injury(STBI),in order to provide reference for clinical diagnosis and treatment.In the clinical diagnosis and treatment of patients with severe craniocerebral trauma,In the case of hypernatremia in patients,it is necessary to promptly intervene,causing physicians to pay attention to electrolytes in clinical diagnosis and treatment.METHODS: Patients with severe craniocerebral trauma who were hospitalized in the Department of Neurosurgery and ICU of the People’s Hospital of Tibet Autonomous Region from 2013.09 to 2017.12(Grass score ≤8)were screened by inclusion criteria and exclusion criteria.Patients who met the criteria were determined according to the criteria.Blood sodium,divided into normal group(<150mmol / L),mild high sodium(150 ~ 155 mmol / L),moderate high sodium(156 ~ 160 mmol / L),severe high sodium(≥ 161 mmol / L)Through statistical analysis of the presence or absence of hypernatremia and varying degrees of hypernatremia on the severity of the patient’s condition,prognosis and mortality.Results: 1.In this study,175 patients with severe craniocerebral trauma,the relationship between GCS score and blood sodium was analyzed by spearman correlation,P=0.00,which was statistically significant.2.In 175 patients with severe craniocerebral trauma,the relationship between serum sodium level and discharge GOS score was analyzed by spearman correlation,P=0.00,which was statistically significant.3.Taking the death of severe craniocerebral patients as the dependent variable,the patient’s age,gender,blood sodium level,admission GCS score as independent variables,Logistic regression analysis was used to find independent risk factors affecting the death of sTBI patients,Logistic regression analysis The results showed that the blood sodium level and admission GCS score P were less than 0.05,which was statistically significant.Conclusions: 1.The lower the GCS score of admission is negatively correlated with the blood sodium level of the patient,that is,the lower the GCS score at admission,the higher the blood sodium level of the patient.2.The blood sodium level was negatively correlated with the discharge GOS score,that is,the higher the blood sodium level,the lower the GOS score when the patient was discharged,that is,the worse the prognosis.3.Blood sodium levels and admission GCS scores are independent risk factors affecting the patient’s death.