Clinical Research Status Of Yu-Jiang Detoxification Mixture Lavatory Nasal Sinus Treatment Of CRS

Chronic rhinosinusitis(CRS) is a common otorhinolaryngology head and neck surgery disease.The main clinical manifestations are nasal obstruction and purulent discharge.It can be accompanied by dizziness,headache,loss of olfactory function or memory decline.At present,the exact pathophysiology of CRS is not yet clear.Domestic and foreign scholars mainly have the following studies:1.Pathogenic microbial infection;2.Allergic reaction;3.Bacterial biofilm;4.Anatomical dysfunction of nasal cavity;5.Dysfunction of cilia movement and so on.Although modern medicine has many treatments for CRS.But there are still many patients after systematic treatment can not achieve long-term satisfactory results.It can only temporarily relieve the clinical symptoms,and the disease can not be cured.CRS belongs to the category of "Nasosinusitis " in traditional Chinese medicine.It's etiology and pathogenesis are divided into two aspects: deficiency syndrome and real syndrome.The real syndrome can be seen in the lung meridian wind-heat,spleen meridian damp-heat and gallbladder-fu stagnation-heat type.Deficiency syndrome can be seen in spleen and stomach weakness,lung qi deficiency and cold,etc.Therapeutic methods include traditional Chinese medicine decoction,acupuncture,acupoint application,nose dropping,stuffing and nose fumigation,etc.Because of its simple operation and definite curative effect,nasal drip is more acceptable to patients.And nose dropping method through nasal mucosa direct drug use,not only can treat local,but also can act on the whole body,so that the whole and local combination.Nose dropping can be extended to rinse,inhalation,fumigation and lavage of traditional Chinese medicine.The lavage of traditional Chinese medicine uses its own devices and methods.And on the basis of nasal irrigation,the drug solution was retained in the sinus cavity to achieve long-term efficacy and lasting effect.It has the characteristics of high bioavailability,simplicity,convenience,wide range of action and few side effects.Professor MAO dehong thinks that the main responsibility of the person with nose yuan lies in the steaming on the meridian of the internal organs and heat,blocking the nasal orifices,and stopping the accumulation of body fluid,so he developed the Yu-jiang detoxification mixture for nasal-sinus lavage treatment,instead of oral Chinese medicine decoction.Clinical studies have found that the Yu-jiang detoxification mixture can wash nasal-nasal sinuses,not only to expel pus,but also to clear the lung,spleen,gallbladder and other visceral heat toxins,in order totreat internal and external causes.Clinical studies have shown that the use of fish sauce detoxification mixture for nasal sinus lavage can effectively promote the elimination of nasal mucosal swelling,reduce inflammation,promote ciliary movement,repair pathological mucosa and alleviate nasal congestion.