| Objectives:To explore whether there were differences of clinical features,TCM constitution and personality characteristics between obese and non-obese patients with polycystic ovary syndrome and the similarities and differences between the two.It was expected to provide objective basis of individualized treatment and nursing for two different types of patients with PCOS Methods:After consulting the relevant domestic and foreign literature,the diagnostic criteria,inclusion and exclusion criteria were established and the questionnaires were designed according to the research content.The patients with PCOS who had been diagnosed in affiliated hospital of Chengdu university of TCM were investigated for this study.After these patients having filled out the "General Survey Form","TCM Constitution Survey" and " Simple Scale China Edition of Eysenck Personality Questionnaire",the data of survey was entered into Excell and imported into SPSS22.0 for data analysis.Results:1.A total of 237 questionnaires were handed out in this study and 12 incomplete questionnaires cases were excluded.The remaining 225 were divided into 104 obese PCOS patients and 121 non-obese PCOS patients according to BMI.There were no statistical differences in age,smoking,drinking history,disposable plastic tableware using,bedtime and gynecologic oncology,mother/sister(before 40 years old)irregular menstruation of family disease history between two groups(P>0.05).The differences of dietary habits,exercise,stress,diabetes,hypertension,obesity,and male early baldness of family disease history were statistically significant between the two groups(P<0.05).2.There were no statistical differences in hairy disease,FSH,E2,P,PRL in basic blood hormone and 2h INS betweed two groups(P > 0.05).The differences ofmenstrual situation,hemorrhoids,LH,LH/FSH,T,FT in basic blood hormone and INS,1h INS,3h INS were statistically significant between the two groups(P<0.05).3.The differences of TCM constitution were statistically significant between the two groups(P<0.05).The distribution of the TCM constitution of the obese group by descending order : phlegmy wet mass(27.9%),qi stagnation(17.3%),yang deficiency(13.5%),wet and hot quality(12.5%),qi deficiency(9.6%),blood stasis(7.7%),yin deficiency(6.7%),peaceful constitution(2.9%),special constitution(1.9%).The distribution of the TCM constitution of the non-obese group by descending order:yang deficiency(25.6%),wet and hot quality(17.4%),phlegmy wet mass(12.4%),qi deficiency(11.6%),qi stagnation(9.1%),blood stasis(8.3%),yin deficiency(7.4%),peaceful constitution(5.0%),special constitution(3.3%).4.The difference of neurotic subscale.in personality traits was statistically significant between the two groups(P < 0.05)and the remaining subscales had no statistically significant differences between the two groups(P>0.05)。Conclusions:1.Unreasonable diet,exercise habits,more serious stress feelings and family history of hypertension,diabetes,obesity,male early baldness may be factors influencing the onset of obesity PCOS.2.The clinical characteristics of the two groups were different.The obesity-type PCOS was dominated by high insulin and high androgen abnormalities and the non-obese group was dominated by LH and LH/FSH abnormalities.The degree of menstrual disorders and the incidence of acne in obese PCOS were higher than those in non-obese PCOS patients.3.The distribution of TCM constitution of two groups had their own characteristics.The obese PCOS patients were more common with phlegmy wet mass,qi stagnation and yang deficiency.The non-obese PCOS patients were more common with yang deficiency,wet and hot quality and phlegmy wet mass.It was indicated that phlegmy wet mass,yang deficiency,qi stagnation and wet and hot quality were good physiques of PCOS.4.The obese PCOS patients were more prone to emotional instability thannon-obese PCOS patients such as stress,anxiety,depression,hyperactivity,etc. |
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