Clinical Study On Tcm Syndrome Distribution Of Chronic Atrophic Gastritis

Objective:The purpose of this study is to explore the regularity of TCM syndrome differentiation and type distribution of 180 cases of chronic atrophic gastritis,and to study the correlation between its distribution,gender,age,helicobacter pylori infection,bile reflux and mucosal atrophy,so as to provide certain reference for the standardization of TCM syndrome type distribution of chronic atrophic gastritis.Methods: 180 patients with chronic atrophic gastritis were definitely diagnosed by clinical retrospective study.The gender,age,discomfort symptoms,course of disease,gastroscopy report,helicobacter pylori test results and pathological examination report of the patients were recorded.Excell table was used to establish the database,and the method of syndrome differentiation for treatment was used to conduct TCM syndrome differentiation and classification.By using chi-square test,descriptive analysis and other methods,the distribution rules of TCM syndromes in chronic atrophic gastritis were summarized,and the correlation between the distribution of TCM syndromes and gender,age,helicobacter pylori infection,bile reflux and gastric mucosa atrophy was described.Results: 1.180 cases were divided into 6 types according to syndrome differentiation,and the specific number distribution of each type was as follows: 67 cases with weak spleen and stomach(including deficiency and cold of spleen and stomach),accounting for 37.2%;45 patients with stomach Yin deficiency syndrome,accounting for 25%;There were 23 patients with liver and stomach qi stagnation syndrome,accounting for12.8%.19 patients with damp-heat syndrome of spleen and stomach,accounting for 10.5%.There were 16 patients with liver-stomach heat retention syndrome,accounting for 8.9%.There were 10 patients with gastric collaterals blood stasis,accounting for 5.6%2.Among the 180 cases,78 were males and 102 were females,with males accounting for 43.3% and 56.7% of the total cases,and the ratio of male to female was 1:1.31.The syndromes of dampness-heat syndrome of spleen and stomach,liver-stomach stasis syndrome and liver-stomach deficiency syndrome were mostly seen in male patients,and the syndromes of liver-stomach qi stagnation syndrome and stomach Yin deficiency were mostly seen in female patients.There was statistical significance between the distribution of each syndrome type and gender(P < 0.05).3.in terms of the age distribution of onset,the number of patients between 45 and 59 years old(that is,middle age)is the highest,up to91,accounting for 50.6% of the total cases,followed by 60 to 89 years old(old age),up to 63,accounting for 35%.The lowest age of onset was28 and the highest was 79.The duration of the disease is usually 1-10 years.4.in all TCM syndromes,spleen and stomach damp-heat syndromes were mostly in the 41-50 year-old group,accounting for 6% of the total cases;Liver and stomach qi stagnation syndrome was mostly in the 51-60 year old group,accounting for 13% of the total cases.Blood stasis of stomach collaterals occurred between 41 and 60 years old,accounting for6% of the total cases.Liver and stomach heat retention syndrome was mostly in the 41-60 year old group,accounting for 8% of the total cases.The syndrome of spleen and stomach weakness(including deficiency and cold of spleen and stomach)mostly occurs in the population over 51 years old,accounting for 36% of the total cases.Syndrome of deficiency of stomach Yin is more common in 51 years old and above;There was a statisticaldifference between the distribution of each syndrome type and the age group(P < 0.05).5.among the 180 cases,26 cases were associated with bile reflux,accounting for 14.4% of the total.The liver and stomach qi stagnation type with bile reflux accounted for the highest proportion,accounting for 43.5% of the syndrome type.There was a statistical difference between the syndrome type and bile reflux(P < 0.05).6.among 180 cases,76 cases were HP positive,accounting for 42.2%of the total cases.The infection rate of spleen and stomach damp-heat type with Hp was the highest,up to 84.2%.Among the other five syndromes,there were more HP positive patients with liver-stomach heat retention syndrome and liver-stomach qi stagnation syndrome.There were more HP negative patients with spleen and stomach weakness(including spleen and stomach deficiency and cold),stomach collaterals blood stasis and stomach Yin deficiency.There was a statistical difference between syndrome type and HP infection(P < 0.05).7.Among the 180 cases,mild to moderate mucosal atrophy was the most common,while severe atrophic gastritis was relatively rare.Spleen and stomach weak(including the spleen and stomach cold),liver and stomach,liver stomach wind-cold type,spleen and stomach syndrome is given priority to with mild-to-moderate atrophy,and more severe contraction in stomach Yin deficiency type,gastric collaterals blood stasis type,the mucosa atrophy appears at the same time,most of the accompanied by the change of intestinal metaplasia,between each card type distribution and mucosal atrophy was statistically significant(P < 0.05),between syndrome and intestinal metaplasia there is no statistical significance(P > 0.05).Conclusion:(1)the most common TCM syndromes of chronic atrophic gastritis are weak spleen and stomach(including deficiency and cold);(2)the disease occurs in the elderly;(3)liver and stomach qi stagnation and deficiency of stomach Yin were more common in female patients,while spleen and stomach damp-heat syndrome and liver-stomach heat retention syndrome were more common in male patients.(4)the infection rate of spleen and stomach damp-heat type with Hp was the highest;(5)bile reflux was most common in liver and stomach qi stagnation type;(6)TCM syndrome differentiation of chronic atrophic gastritis is correlated with gender,age,helicobacter pylori infection,bile reflux,and mucosal atrophy,and there is a certain correlation.There is no correlation between TCM syndrome differentiation and intestinal metaplasia.