Study On The Distribution Of Syndrome Types And Related Factors In Patients With Chronic Atrophic Gastritis

Objective: To analyze the syndrome manifestations of 260 patients with chronic atrophic gastritis(CAG)and summarize the distribution of TCM syndro me types,so as to understand the etiology and pathogenesis characteristics of the disease and the distribution of TCM syndrome types.The treatment and prevention of atrophic gastritis provide further support and guidance.Methods: 260 patients with chronic atrophic gastritis who met the inclusion criteria were selected clinically,and count the gender,age,Helicobacter pylori(HP)infection,degree of atrophy,range of atrophy,constitution types,and TCM syndromes of 260 patients with chronic atrophic gastritis.And analyze the correlation between syndrome types and other factors.Use SPSS21.0 statistical software to do statistical analysis on the data and draw corresponding conclusions.Results: Among the 260 patients with chro nic atrophic gastritis included in this study,the youngest was 27 years old and the oldest was 70 years old,with an average age of(53.87±8.86)years.Among them,110 were males(42.7%)and 150 were females(57.3%).The ratio of male to female was about 1:1.36,mainly middle-aged and elderly over 50 years old;The distribution of TCM syndromes in descending order was spleen and stomach damp-heat syndrome>spleen and stomach weakness syndrome>stagnation of liver and stomach qi syndrome> stagnation of liver and stomach heat syndrome>insufficiency of stomach yin syndrome> stomach collateral blood stasis syndrome,and the difference in the distribution of the number of different syndrome types is statistically significant(P=0.000 < 0.05);HP infection positive group syndrome types are distributed as follows: spleen and stomach damp-heat syndrome>spleen and stomach weakness syndrome= liver and stomach stagnation heat syndrome> liver and stomach qi stagnation syndrome>stomach yin deficiency syndrome>stomach collateral blood stasis syndrome,HP infection negative group syndrome types are distributed as follows: spleen and stomach weakness syndrome>spleen-stomach damp-heat syndrome>stagnation of liver and stomach qi syndrome>liver-stomach stagnation heat syndrome= stomach yin deficiency s yndrome>stomach collateral stasis blood syndrome,and the distribution difference between the two groups is statistically significant(P < 0.05);The distribution of the syndrome types of mild atrophy is: spleen and stomach damp-heat syndrome> spleen and stomach weakness syndrome>liver and stomach qi stagnation syndrome> liver and stomach stagnation-heat syndrome> stomach yin deficiency syndrome> stomach collateral blood stasis syndrome,and the distribution of moderate atrophy syndrome types a re in sequence : spleen and stomach weakness syndrome> spleen and stomach damp-heat syndrome> liver and stomach qi stagnation syndrome> liver and stomach stagnation heat syndrome> stomach yin deficiency syndrome> stomach collateral blood stasis syndrome,and the distribution of the syndrome types of severe atrophy is as follows: stomach collateral blood stasis syndrome> stomach yin deficiency syndrome> spleen and stomach weakness syndrome> liver and stomach qi stagnation syndrome> spleen and stomach damp-heat syndrome = liver and stomach stagnation-heat syndrome,and the distribution difference between the three groups is statistically significant(P < 0.05);C1-C2 atrophy range syndrome distribution: spleen and stomach damp-heat syndrome syndrome>spleen and stomach weakness syndrome>stagnation of liver and stomach qi syndrome>stagnation of liver and stomach heat syndrome>stomach yin deficiency syndrome>stomach collateral blood stasis syndrome,and the distribution of syndrome types of C3-O1 atrophy: spleen and stomach weakness syndrome>hepatic stagnation heat syndrome>spleen and stomach damp-heat syndrome liver and stomach qi stagnation syndrome> stomach yin deficiency syndrome> stomach collateral blood stasis syndrome,O2-O3 atrophy range of syndrome distributi on: stomach collateral stasis blood syndrome> stomach yin deficiency syndrome> spleen and stomach damp-heat syndrome> spleen and stomach weakness syndrome= liver and stomach qi stagnation syndrome>liver and stomach stagnation-heat syndrome,and the distribution difference between the three groups is statistically significant(P < 0.05);The constitution distribution of patients with chronic atrophic gastritis: damp-heat=qi deficiency>phlegm-dampness=yin deficiency>blood stasis>yang deficiency>qi stagnation=special>general,and the difference in the distribution of the number of people between different constitution is statistically significant(P=0.000 < 0.05);The distribution of syndrome types may have a certain relationship with the distribution of constitution for chronic atrophic gastritis.Specifically,in the syndrome of liver and stomach qi stagnation,the distribution of qi deficiency and yang deficiency are the main factors,and in the spleen and stomach weakness syndrome is mainly based on the distribution of qi deficiency and yang deficiency,and in the spleen and stomach damp-heat syndrome,phlegm-dampness and damp-heat are mainly distributed,and in the stomach-yin deficiency syndrome,the yin-deficiency is mainly divided,and in the stomach-collateral blood stasis syndrome is mainly in the distribution of blood stasis.Conclusion: 1.Chronic atrophic gastritis is mainly affected by middle-aged and elderly patients(51-60)years old,and age is one of the factors affecting the onset of the disease;2.Weakness of the spleen and stomach(spleen and stomach deficiency and cold)and spleen and stomach damp-heat chronic atrophic gastritis has more than half of the main types of syndromes;3.The distribution of TCM syndromes of chronic atrophic gastritis is indeed affected by HP infection,with the most significant impact on the spleen and stomach damp-heat syndrome;4.Chronic atrophic gastritis is different between the degree and scope of atrophy,the distribution of syndrome types has a certain difference;5.Chronic atrophic gastritis is high in damp-heat and qi deficiency,and the distribution of syndrome types may be related to the consititution distribution.