Effects Of Moxibustion Therapy On The Symptoms And Sex Hormone Levels In Perimenopausal Patients

ObjectiveThis study sets perimenopausal syndrome patients as observation object,oral kuntai capsule,moxibustion and moxibustion combined with oral kuntai capsule were studied.To evaluate the clinical effect of moxibustion on perimenopausal syndrome,to provide some clinical evidence for the study of moxibustion for perimenopausal syndrome.MethodsThe patients with perimenopausal syndrome were randomly divided into control group,test group 1 and test group 2?30 cases in each group?.In the control group,oral kuntai capsule was taken,and the moxibustion method was used in the experiment group 1,The experiment group 2 were combined with moxibustion and oral kuntai capsule.Moxibustion method adopts mild moxibustion,and it is selected as guan yuan,sanyin jiao?both sides?,shenshu point?bilateral?.Each acupuncture point moxibustion 10 minutes,with heat on the patients'local skin until the consciousness of mediate warmness,once a day;Oral kuntai capsule method is administered uniformly,four at a time,three times a day;moxibustion method combined with oral kuntai capsule is the combination of the above two methods.The three groups were treated for three weeks with one course of treatment,one week of rest,three courses of treatment and 12 weeks follow-up after the end of the treatment.Before treatment,4 weeks,12 weeks of treatment and follow-up of 12 weeks after treatment,respectively,record the patient's quality of life scale perimenopausal score?MENQOL?,menopause symptoms rating scale score?Kupperman score,KMI?;the serum sex hormone levels?FSH and E₂?of the patients were examined before and 12 weeks of treatment and 12 weeks after treatment,and the data were statistically analyzed.Result1.MENQOL,KMI score:MENQOL score and KMI score were decreased in the three groups after 4 weeks,12 weeks and 12 weeks after treatment,and the difference was statistically significant?P<0.05?.Compared with the treatment of 4 weeks,the score of 12weeks was still decreased,and the difference was statistically significant?P<0.05?.There was no significant difference in efficacy between 12 weeks of treatment and 12 weeks after treatment?P>0.05?.Comparison of three groups of time points,there was no significant difference in the therapeutic effect at 4 weeks?P>0.05?.There was no significant difference between the control group and the test group 1?P>0.05?,the difference between the test group 2 and the control group was statistically significant?P<0.05?,the difference between the test group 2 and test group 1 was statistically significant?P<0.05?.2.MENQOL four dimensional comparisons:Compared to before treatment,the scores of the three groups in the four dimensions were decreased in the three groups after 4 weeks,12weeks and 12 weeks after treatment,and the difference was statistically significant?P<0.05?.Compared with treatment of 4 weeks,the scores of the three groups with treatment of12 weeks in the four dimensions continued to decline,and the differences were statistically significant?P<0.01?.Compared with treatment of 12 weeks,the control group had statistically significant differences in sex life after 12 weeks after treatment?P<0.01?.There were no statistically significant differences in the other three dimensions of the control group,as well as the four major dimensions of the test group 1 and the test group 2?P>0.05?.Three groups of four dimensions were compared:4 weeks of treatment,no statistically significant difference between the three groups?P>0.05?.In the treatment of 12 weeks,there were statistically significant differences in the three dimensions of vasoconstriction,mental state and sexual activity between the test group 2 and the other two groups?P<0.05?.3.Serum sex hormone levels:The FSH value of serum FSH was slightly fluctuated in the three groups before and after treatment,but the difference was not statistically significant?P>0.05?.The E₂ values increased at 12 weeks in all three groups,the difference was statistically significant?P<0.05?.Compared with the treatment of 12 weeks,the E₂ values were fluctuated at 12 weeks after treatment in the three groups,but the difference was not statistically significant?P>0.05?.Comparing with the state both moxibustion group and oral kuntai capsule group were treated for 12 weeks of treatment,and the serum E₂ value of the patients increased,and the difference was not statistically significant?P>0.05?,however,the combined treatment of the two groups was compared with moxibustion group,oral kuntai capsule group for 12 weeks of treatment,and the serum E₂ values of patients were both increased,and the differences were statistically significant?P<0.05?.Conclusion1.The combination of moxibustion therapy,oral kuntai capsule and moxibustion therapy combined with oral kuntai capsule can improve the perimenopausal symptoms,moxibustion therapy and oral kuntai capsule have the same therapeutic effect.2.With the extension of the treatment cycle,oral kuntai capsule combined with moxibustion therapy has a significant effect on improving the patients'vasoconstriction,mental state and sexual life.3.Moxibustion therapy is more effective in improving perimenopausal symptoms and improving the quality of life of patients.4.The combination of moxibustion therapy,oral kuntai capsule and moxibustion therapy combined with oral kuntai capsule can significantly improve perimenopausal symptoms and may be related to elevated serum E₂ level.In ascending patients E₂ level,the combination of the two was better than the oral kuntai capsule group and moxibustion therapy group.