The Clinical Study Of Tonglin Paishidecoction In The Treatment Of Residual Calculus After Urinary Caleuli Operation

ObjectiveIn this research,intervention of oral tonglupaishi decoction was given to patients with residual stones after urinary calculi surgery,to observe the effectiveness and safety of the treatment of postoperative residual calculus.MethodsA total of 60 cases of kidney stone residuals after urolithotripsy(percutaneous nephrolithotomy and ureteroscopy)in the department of urology of shenzhen hospital of traditional Chinese medicine from March 2018 to March 2019 were selected as research objects.According to the random number table method,the patients were randomly divided into two groups:the experimental group(tonglin paishi decoction combined with conventional treatment)and the control group(conventional treatment),with 30 cases in each group.Patients included in the study received routine postoperative bed rest,enhanced symptomatic treatment such as anti-infection and fluid rehydration.Urinary catheter was removed on the first day after surgery,KUB was reexamined on the second day after surgery,renal fistula was removed on the fourth day(patients after percutaneous nephroscopy),and double J tubes were removed 4 weeks after surgery.In the experimental group,the oral administration of traditional Chinese medicine was started after the residual calculus was found by the postoperative review of KUB.Drug composition:christina loosestrife herb 30g,spora Lygodii 20g,endothelium corneum gigeriae galli 20g,herba pyrrosiae 15g,achyranthes bidentata 15g,pseudo-ginseng 15g,radix paeoniae rubra 15g,peach kernel 10g,astragalus 25g,immature bitter orange 10g,plantain seeds 20g,licorice 5g,radix rehmanniae 15g.150ml water was decocted with 2 doses/day(morning and evening)for 8 weeks.Patients in the two groups were also instructed to drink more than 2000ml of water every day.After the removal of the double J tube,patients in the two groups were instructed to perform jumping exercises 3 times a day for 5min each time.KUB was reviewed after 4 weeks and 8 weeks of treatment,the location of residual stones,clinical symptoms,clinical efficacy,and any adverse reactions and side effects occurred during the test were recorded.SPSS 23.0 statistical software was used for analysis,and different statistical methods were adopted according to different data.Independent sample t test,chi-square test and rank sum test were used to estimate the differences between the two groups.ResultsThe results showed that:(1)before treatment,there was no statistically significant difference in general data such as age and course of disease between the two groups.(2)after 4 weeks of treatment,the recovery rate,effective rate and total effective rate of the two groups were:3.33%,23.33%and 73.33%of the experimental group,and 3.33%,10.00%and 86.67%of the control group,respectively.The above three data between the two groups were statistically calculated,and the difference was not statistically significant.(3)after 8 weeks of treatment the recovery rate,effective rate and total effective rate of the two groups were 30.00%,46.67%and 23.33%of the experimental group,and 3.33%,16.67%and 80.00%of the control group,respectively.After statistical calculation of the above three data between the two groups,the differences were statistically significant.It can be considered that after 8 weeks of treatment,the efficacy of the experimental group is better than that of the control group.(4)With few adverse reactions,we found 1 case of diarrhea occurred in the experimental group,and 1 case of diarrhea and 1 case of constipation occurred in the control group.There was no statistically significant difference between the two groups,and the two groups had high safety in treatment.ConclusionTonglin paishi decoction has no obvious advantage over the control group in the efficacy within 4 weeks after the operation without the removal of the double J tube.After 8 weeks of treatment,the effect of the treated group was significantly better than that of the non-treated group.Therefore,tonglin paishi decoction is effective in the treatment of postoperative residual stones,and it was convenient to take,low price and high safety.So it is recommended for clinical promotion.