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Effect Of Enhanced Recovery After Surgery On Postoperative Rehabilitation Of Patients With Colorectal Cancer

Posted on:2019-05-13Degree:MasterType:Thesis
Country:ChinaCandidate:W GengFull Text:PDF
GTID:2404330572951203Subject:Public Health
Abstract/Summary:PDF Full Text Request
Surgical treatment is the main treatment for colorectal cancer,but the problems such as large postoperative stress response,slow postoperative recovery,and postoperative complications are also exist.The concept of enhanced recovery after surgery(ERAS)was proposed by Danish doctor Henrik Kehlet in 1997,and has been promoted vigorously in European and American countries in recent years.The concept of ERAS is different from the traditional perioperative surgical treatment,which changes the treatment mode of some diseases.Many literatures have reported that the concept of enhanced recovery of surgery program has achieved good clinical results in the surgical treatment of patients with colorectal cancer and increased the satisfaction of patients.The application of enhanced recovery of surgery program in surgery is an inevitable trend of medical progress and social development.In this study,a large general hospital was selected to investigate the patients with colorectal cancer who were hospitalized in gastrointestinal surgery,and the preoperative and postoperative conditions of the group with enhanced recovery of surgery program and the control group with traditional treatment mode were observed to provide basic evidence for the better application of enhanced recovery after surgery in clinical colorectal surgery.Objective:Analyze and compare the effects of enhanced recovery of surgery program and traditional treatment mode on the treatment of patients with colorectal cancer,and explore the advantages of enhanced recovery of surgery program.Methods:A total of 268 patients with colorectal cancer who underwent gastrointestinal surgery in the First Hospital of Jilin University from January 2017 to December 2017 were selected as objects.According to different perioperative treatment measures,the ERAS group for enhanced recovery of surgery program and the control group for traditional nursing measures were divided.Among them,178 patients in the ERAS group of rapid rehabilitation surgery and 90 patients in the control group with traditional nursing measures.The ERAS group of enhanced recovery of surgery program used laparoscopic minimally invasive surgery to optimize preoperative bowel preparation,optimized intraoperative anesthesia and analgesia,unconventional gastrointestinal decompression,unconventional abdominal drainage tube,and postoperative rehabilitation treatment,early bed-out activities,early eating,discharge standards can be discharged.The control group was given traditional treatment and care measures.The postoperative pain digital score(NRS),the first postoperative deflation and defecation time,the time of getting out of bed,the length of hospital stay,postoperative medication,postoperative drainage tube use,preoperative and postoperative were compared between the two groups.Albumin levels,hospitalization costs,and complications.The collected data were analyzed using spss21.0 statistical analysis software.The normal distribution of the variables was expressed as(?X ± S),the first postoperative exhaust and defecation time,the time of getting out of bed,hospitalization time,postoperative medication and other indicators The t test was used to compare the preoperative and postoperative albumin levels with repeated measures of variance analysis;the postoperative drainage tube use the Rank sum test;variables that did not conform to the normal distribution were expressed by median and quartile(M,IQR).Rank sum test was used;count data such as the past history of the two groups of patients and postoperative complications were compared using the test or Fisher's exact probability method.All statistical tests were two-sided and the statistical test level was =0.05.Results:In this research,a total of 268 patients with colorectal cancer hospitalized in the Department of Gastrointestinal Surgery were investigated.Among them,178 patients in the rapid rehabilitation surgery ERAS group and 90 patients in the open surgery group.The general comparison between the two groups,including gender,age,past history,and surgical site,was comparable(P>0.05).Compared with the control group,the postoperative hospitalization time of the two groups was shorter than that of the control group.The postoperative drinking time was advanced,the postoperative diet time was advanced,the first exhaust time was advanced,and the first defecation time and postoperative time were postoperative.Bed activity time was advanced and hospitalization expenses were reduced(P<0.05).There was no significant difference in preoperative albumin between the two groups(P>0.05).The albumin level in the ERAS group was higher than that in the control group(P<0.05).The number of antibiotics used in the ERAS group,the number of days of parenteral nutrition and the number of days of antipyretics were lower than those of the control group(P<0.05).The use rate of postoperative painkillers in the ERAS group was lower than that in the control group(P<0.05).The postoperative pain scores of the two groups were compared.The pain in the ERAS group was lighter than that in the control group(P<0.05).The number of drainage tubes used in the ERAS group and the control group was reduced,and the total extraction time of the drainage tube was advanced(P<0.05).The incidence of postoperative pulmonary infection,anastomotic leakage,wound infection,inferior vena cava thrombosis and chyle in the ERAS group was lower than that in the control group(P<0.05).Conclusion:1.Enhanced recovery after surgery is conducive to rapid recovery after surgery;2.Enhanced recovery after surgery can reduce postoperative pain of patients;3.Enhanced recovery after surgery can shorten the number of hospital stays after surgery and save medical costs;4.Enhanced recovery after surgery is safe for patients with colorectal cancer and does not increase the incidence of postoperative complications in patients with colorectal cancer.
Keywords/Search Tags:Enhanced recovery after surgery, colorectal cancer patients, postoperative rehabilitation
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