Clinical Observation On Treatment Of Qi Deficiency And Phlegm And Blood Stasis Type Of Ventricular Arrhythmia (Ventricular Premature And Paroxysmal Ventricular Tachycardia) Taking Tiaolv Ningji Decoction

ObjectiveThrough the clinical observation of 24-hour Holter total heart rate,premature beats,and short ventricular tachycardia and TCM syndrome score in patients who had been taken Tiaolv Ningji Decoction with Qi deficiency and phlegm and blood stasis type of ventricular arrhythmia(ventricular premature and paroxysmal ventricular tachycardia),we investigate the effectiveness and safety of Tiaolv Ningji Decoction in the treatment of qi-deficiency and qi-negative ventricular arrhythmias,to find theoretical basis,treatment ideas and methods for the treatment of ventricular arrhythmia by Chinese medicine.MethodsWe selected 62 patients with Qi phlegm diagnosed ventricular arrhythmia(ventricular premature and paroxysmal supraventricular tachycardia),randomized into treatment group and in control groupwith each 31 cases,The treatment group took Tiaolv Ningji Decoction 2 times warm water daily;the control group received metoprolol(metoprolol succinate sustained-release tablets)with 47.5mg each time once daily;the treatment period was 4 weeks.Observe and compare the intragroup changes and intergroup differences among baseline changes,baseline ECG,24-hour dynamic electrocardiogram,and TCM clinical symptom scores pre and post treatment,and compare the safety pre and post treatment with blood,urine,feces,liver and kidney function.All data were analyzed.Results1.Holter Comparison of efficacy:the number of premature beats,pair ventricular premature,bigeminy,trigeminy and non-sustained ventricular tachycardia were significantly different(P<0.05)within the group before and after treatment;there was a significant difference in the total number of heartbeats(P<0.05).There was no significant difference between the groups(P>0.05).2.Comparing ECG effects:There was significant difference between the two groups before and after treatment(P<0.05);there was no significant difference between the two groups(P>0.05).3.Comparison of the efficacy of TCM syndromes:There were significant differences between the groups within the total group of TCM syndromes(P<0.05).4.safety observation:the two groups of vital signs,hematuria,faecal routine,liver and kidney function were not abnormal,and had good safety.Conclusion1.The treatment group had obvious advantages in controlling the number of premature beats and non-sustained ventricular tachycardia,and there was no statistical difference between the control of heart rate and the total number of heart beats in the control group,the results showed that Tiaolv Ningji Decoction was better than Betaloc in the treatment of qi deficiency and ventricular arrhythmia(ventricular premature and paroxysmal ventricular tachycardia).and the difference in heart rate control is not significant.2.Tiaolv Ningji Decoction can significantly improve the clinical symptoms of patients with qi-deficiency and phlegm-associated ventricular arrhythmias(ventricular premature and paroxysmal ventricular tachycardia),and has a good therapeutic effect.3.Tiaolv Ningji Decoction has good safety in the treatment of ventricular arrhythmias(ventricular premature and paroxysmal ventricular tachycardia),and has clinical value.