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Application Of Enhanced Recovery After Surgery In Patients With Colorectal Cancer Perioperative

Posted on:2019-12-07Degree:MasterType:Thesis
Country:ChinaCandidate:Y C SunFull Text:PDF
GTID:2404330548956362Subject:Oncology
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Objectives: To investigate the ERAS on postoperative clinical indicators and postoperative stress in colorectal cancer patients,by comparing of enhanced recovery after surgery and traditional methods in colorectal cancer patients.Methods: A total of 65 patients,from March 1,2016 to December 31,2016,that have undergone radical surgery for colorectal cancer in our hospital of gastrointestinal surgery were selected for research.Patients enrolled in the standard randomization were randomly assigned to two groups: ERAS group(33 cases,treated by ERAS concept in perioperative period)and control group(32 cases,treated by traditional processing scheme in perioperative period).Observing the postoperative recovery,stress,complications and postoperative hospital stay,costs and so on.Results: In these two different groups showed the time to first bed ambulation in ERAS group was(2.5 ± 1.9)d,which was greatly shorter than that in control group(4.6 ± 1.6)d,P <0.001;the time of the first anal ventilation was(3.1 ± 1.4)d,which was greatly shorter than control group(4.4 ± 1.5)d,P = 0.010;The postoperative hospital stay was(7.2 ± 4.1)d,which was significantly shorter than that of the control group(9.8 ± 2.2)d,P <0.001;the hospitalization expenses were(6.3 ± 1.2)ten thousand yuan,significantly less than the control group,(7.2 ± 1.5),P = 0.040;The postoperative NRS pain score was(1.7 ± 0.8)points also declined when compared with the control group(3.4 ± 0.6)points,P = 0.012;the incidence of complications of these two groups were 12.1%(4/33),18.7%(6/32),P = 0.46,respectively.Comparing the number of white blood cells,blood glucose,and C-RP in the first day?third day after operation in the ERAS group with the control group(P<0.05),there is no statistical significance.Comparing the number of re hospitalization 30 days later and the quality of life test scores between the two groups after operation,P > 0.05,there is no statistical significance.Conclusion: ERAS can accelerate postoperative rehabilitation,reduce postoperative stress response,shorten the hospital stay,ease the financial burden of medical treatment,decrease the postoperative complications,and it is effective and feasible to be applied of colorectal cancer patients in perioperative period.
Keywords/Search Tags:enhanced recovery after surgery, colorectal cancer, postoperative stress, postoperative rehabilitation
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