Observation On Curative Effect Of Moxibustion With Ginger On Nausea And Vomiting Induced By Platinum Chemotherapy

Objective:Malignant tumor is a major disease threatening human health at present.China is one of the countries with a high incidence of cancer.In the struggle against malignant tumors,chemotherapy plays a vital role,and has been continuously explored for several generations.It has gradually established the irreplaceable position of platinum chemotherapeutic drugs in cancer chemotherapy.However,there are some adverse reactions such as nausea and vomiting in the course of application,which bring inconvenience to the treatment of cancer.Western medicine used tropisetron and other 5-HT3 receptor antagonists to stop emesis,it has achieved certain curative effect in clinic,but the problems such as toxic side effect and high cost of medicine itself can not be ignored.In this study,the nausea and vomiting symptoms of nasopharyngeal carcinoma patients after chemotherapy were treated with ginger moxibustion combined with western medicine antiemetic agents,and compared with the routine use of antiemetic drugs.To observe the clinical effect of ginger moxibustion on nausea and vomiting induced by platinum chemotherapy.Methods:A total of 65 eligible subjects were included in this study,33 cases in the treatment group,32 cases in the control group.Both groups were treated with tropisetron as well as clinical routine treatment.The treatment group combined with ginger moxibustion on this basis,the trial began from the first day of chemotherapy and end at one cycle of chemotherapy,once a day for 3 days,the relative symptoms of eachsubject were recorded objectively and the data were statistically analyzed.The statistical difference was found between the two groups(P<0.05).Finally,the conclusion was drawn.Results:There was no evident difference in the complete remission rate of nausea between the two groups on the first day of chemotherapy,on the Second to fifth days of chemotherapy the difference between the two groups is distinct.In terms of the duration of nausea,the rank sum test was used in the two groups,and the results showed that the difference between the two groups is obvious.KPS were compared between the two groups,the scores of the two groups before and after treatment showed that P<0.05.The incidence of constipation and fatigue were 15.2% and21.2% in the treatment group,40.6% and 46.9 in the control group,respectively,with chi-square test(P<0.05).The two groups were significantly different in the dosage of tropisetron.Conclusion:Ginger moxibustion can availably improve nausea and vomiting symptoms of chemotherapy patients,shorten nausea days,reduce the dosage of antiemetic drugs during chemotherapy,improve symptoms such as fatigue and constipation during chemotherapy,and improve the functional status of patients.To help patients pass the chemotherapy period smoothly.Ginger moxibustion has the advantage of simple operation,non-invasive,safety and patients suffer less,it is worth popularizing.