Study On Improvement Of Rat Stomach Real Cold Syndrome And The Efficacy Of Reducing Blood Fat Via The Fementation Liquid Of Gynostemma

Gynostemma pentaphyllum(Thrunb.)Mak(GP)have the role of tonifying qi,lowering Hyperglycemia,Hyperlipidemia and high blood pressure,known as ginseng growing in the south;However,due to its cold-natured,taken more may cause stomach cold symptoms such as anorexia,;vomit Acid Hydrolysis,this test is proposed to verify whether GP fermented via lactobacillus can avoid the disadvantages,this experiment is proposed in the contrast group in rats experiment;Through contrast test,test and observation of behavior characterization of stomach real cold syndrome rats lavaged by fermentation GP;influence of the hemorheology indexes to the stomach real old syndrome rats;influence of the Liver function index of gastric real cold syndrome rats;influence of the immune indexes of stomach real cold syndrome rats;Expecting they can play a role of protecting gastric mucosa to the real cold syndrome rats stomach gastric;Expecting it has the distinctive features of prevention of stomach cold.Therefore to clinically use GP,to correctly indentify new product research and development,and fully exert the efficacy of GP opened up a new way.Test methods set the blank group,,high-fat diet group,the low concentration GP of total extract group,the high GP of total extract group,low concentration GP fermented(inactivated),high concentration GP fermented(inactivated),low concentration GP fermented(active),high concentration GP fermented(active)natural yogurt(inactivated),natural yogurt(active),egg yolk liquid,egg yolk yogurt,egg yolk GP yogurt.Through the above giving mendicine group,observant of their changes in behavior of Stomach real cold syndrome rats(food intake,body weight,hair color,,mental state);hemorheology indexes by blood rheometer(the whole blood viscosity,whole blood reduction viscosity,plasma viscosity,erythrocyte aggregation index,hematocrit,erythrocyte deformation index,erythrocyte electrophoresis time,ESR equation K value,fibrin original);AST,ALT,CHO,TG,TC,HDL,LDL,Blood sugar,SI,TI,LI.(1)The effects on Behavior Symptoms on Rats:?The appetite on rats:the appetites of the six groups(the low concentration GP of total extract group,the high concentration GP of total extract group,low concentration GP fermented(inactivated),high concentration GP fermented(inactivated),low concentration GP fermented(active),high concentration GP fermented(active))were improved;?The weigh on rats:the weighs of the three groups(the high concentration GP of total extract group,high concentration GP fermented(inactivated),high concentration GP fermented(active))were increased significantly than the high-fat diet group(P<0.05);?The hair colour on rats:the hair color scores of the six groups(the low concentration GP of total extract group,the high concentration GP of total extract group,low concentration GP fermented(inactivated),high concentration GP fermented(inactivated),low concentration GP fermented(active),high concentration GP fermented(active))increased significantly than the high-fat diet group(P<0.01);?The feces on rats:feces of the six groups(the low concentration GP of total extract group,the high concentration GP of total extract group,low concentration GP fermented(inactivated),high concentration GP fermented(inactivated)fe),low concentration GP fermented(active),high concentration GP fermented(active))were decreased,they were relatively dry and had shape;?The state of health on rats:the state of health of the six groups(the low concentration GP of total extract group,the high concentration GP of total extract group,low concentration GP fermented(inactivated),high concentration GP fermented(inactivated),low concentration GP fermented(active),high concentration GP fermented(active))had recovered.(2)The effects on Hemorheology:the whole blood viscosity of the four groups(low concentration GP fermented(inactivated),high concentration GP fermented(inactivated),low concentration GP fermented(active),high concentration GP fermented(active))had been reduced significantly than the high-fat diet group(P<0.05 or P<0.01);Conclusions:1.The HFD in the experiment can significantly increase the BW and serum CHO level,serum TC level,serum TG level,cause severe lesions and high-fat diet in mice,showing that the experimental fatty method was feasible and can meet the demand of our research.