The Clinical Research Of Warming-invigorating Kidney And Stringing Ridge, Dispelling Cold And Activating Blood Circulation For Reatment Conbined With External And Internal Chinese Herbs Of Kidney Deficiency And Cold In Governor Vessel Of Ankylosing Spondy

ObjectiveThis research is for the purpose of discussing warming-invigorating kidney and stringing ridge,dispelling cold and activating blood circulation for treatment conbined with external and internal chinese herbs of kidney deficiency and cold in governor vessel of ankylosing spondylitis the clinical effectiveness,the drug safety and adverse reactions.By setting the control group,crosswise comparing on the effectiveness by contrasting with the treatment group in order to explore the chinese medicine in treating the ankylosing spondylitis safely and effectively.MethodsConforming to the ankylosing spondylitis kidney deficiency and cold in governor vessel patients who 40 examples integrates the standard to divide into two groups stochastically.The treatment group of 20 examples,gives conventional treatment and sulfasalazine and chinese medicine fumigating conbined with decoction of warming-invigorating kidney and stringing ridge,dispelling cold and activating blood circulation.The control group of 20 examples,give conventional treatment and sulfasalazine,and formulate observation table.Through patient symptom improved situation,the Bath disease activity index (BASDAI),Bath functional index (BASFI) and to routine blood test,ESR,CRP,hemorheologic test and so on,and Adopting the ASAS20 and BASDAI50 standards developed by international ASAS Working Group and efficiency of TCM syndromes criteria to evaluate the efficiency of chinese medicine conbined external and internal treatment of AS.ResultsThrough to 40 example patients of 12 week-long observations the chinese medicine conbined external and internal of warming-invigorating kidney and stringing ridge,dispelling cold and activating blood circulation to improve the patient's symptom,the Bath disease activity index(BASDAI),Bath functional index(BASFI),pain,inflammation index and clinical symptoms have shown obvious improvement(P<0.05),ESR,CRP and hemorheologic test were also improved(P<0.05). The treatment group's clinical symptoms improved significantly.Conclusionwarming-invigorating kidney and stringing ridge,dispelling cold and activating blood circulation for treatment conbined external and internal chinese herbs of kidney deficiency and cold in governor vessel of ankylosing spondylitis,regardless of improving the patient symptom,enhanceing life,reduceing the disease activity to have the good curative effect,and its security and the compliance is good,which has certain utilization prospect.