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The Clinical Research On The Effect Of Modified Buyang Huanwu Decoction In Treating Acute Ischemic Stroke(qi-deficiency And Blood-stasis Syndrome)

Posted on:2019-10-12Degree:MasterType:Thesis
Country:ChinaCandidate:L J PeiFull Text:PDF
GTID:2394330566973848Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
Objective: The study was designed to investigate the clinical therapeutic efficacy of modified Buyang Huanwu Decoction in treating acute ischemic stroke(Qi-deficiency and blood-stasis syndrome)and to provide experimental evidence for its clinical application.Methods: With 60 acute ischemic stroke patients were randomly divided into standard observation group(30 cases)and control group(30 cases).After assignment,all the patients were under appropriate control of blood pressure,blood glucose and complications.Patients in the control group were simultaneously orally treated with anti-platelet aggregation,brain cells nourished,the maintenance electrolyte and acid-base balallce and symptomatic treatment.Patients in the observation group were given modified Buyang Huanwu Decoction apart from the regular western medicine.Patients in both groups were continuously treated for four weeks.The clinical efficacy of modified Buyang Huanwu Decoction in treating acute ischemic stroke(Qi-deficiency and blood-stasis syndrome)was evaluated based on the following factors: National Institutes of Health Stroke Scale(NHISS),Modified Barthel Index(MBI),score changes of grading quantification of Chinese Medicine symptoms and variations in serum homocysteine(Hcy),total cholesterol(TC),triglyceride(TG)as well as low density lipoprotein(LDL-C)levels.Results:1.There is no statistically significance in baseline data(P>0.05).2.Comparison of total efficient after treatment:(1)Comparison of the NIHSS of the two groups,the observation group was 100%,the control group was 76.7%,there was statistical difference(P<0.05);(2)Comparison of the Chinese Medicine symptoms of the two groups,the observation group was 90%,the control group was 60%,there was statistical difference(P<0.05);3.In terms of the neurological deficit score(NIHSS),the scores after treatment were lower than those before treatment in both groups,the two groups were statistically significant after treatment(P<0.05),and the score difference the two groups was significant(P<0.05).The results indicated that and the decrease of the observation group was greater than that of the control group,suggesting a superior effect of the treatment group compared to the control group in improving neurological deficits in patients with acute ischemic stroke.4.In terms of daily behavior function,the post-treatment scores were higher than those before treatment in the two groups,the two groups were significantly different after treatment(P<0.05),and the score difference the two groups was significant(P<0.05).The above findings indicated that the degree of improvement in the observation group was greater than that of the control group,indicating a superior effect of the observation group compared to the control group in alleviating daily behavior functions of patients with acute ischemic stroke.5.In terms of the Chinese Medicine symptoms,the scores after treatment were lower than those before treatment in both groups,the two groups were statistically significant after treatment(P<0.05),and the score difference the two groups was significant(P<0.05).The results indicated that and the decrease of the observation group was greater than that of the control group,suggesting a superior effect of the treatment group compared to the control group in terms of alleviating the Chinese Medicine symptoms.6.The levels of Hcy after treatment were lower than those before treatment in both groups,the two groups were statistically significant after treatment(P<0.05),and the difference the two groups was significant(P<0.05).The results indicated that and the decrease of the observation group was greater than that of the control group,suggesting a superior effect of the treatment group compared to the control group in terms of alleviating the level of Hcy.7.The levels of serum lipid(LDL-C,TC and TG)after treatment were lower than those before treatment in both groups,the two groups were statistically significant after treatment(P<0.05),and the difference the two groups was significant(P<0.05).The results indicated that and the decrease of the observation group was greater than that of the control group,suggesting a superior effect of the treatment group compared to the control group in terms of alleviating the level of serum lipid levels.Conclusion: A combination of western medicine with modified Buyang Huanwu Decoction harbored a definitely better effect in patients with acute ischemic stroke(Qi-deficiency and blood-stasis syndrome)without side effects,which deserves promotion.
Keywords/Search Tags:Modified Buyang Huanwu Decoction, acute ischemic stroke, cerebrovascular disease, Qi-deficiency and blood-stasis syndrome
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