| Objective:In recent years,acupoint application therapy has been widely used in various clinical syndromes.It can be used to treat a variety of chronic diseases as well as certain acute disease syndromes.It can be applied not only to viscera syndrome but also to skin surface disorders.Because of its combination of acupoint efficacy and drug efficacy,it not only exerts acupuncture stimulation,but also has the pharmacological effects of using drugs.It also has the combined functions of the former two,and it is simple and safe.Applying or filling drugs into acupuncture points to stimulate the umbilical or let drug absorbed through the umbilicus to treat diseases,it is called Umbilicus therapy or navel therapy.In this experiment,Chinese medicine,western medicine and blank-controlled combined with Danggui yinzi and second-generation H1 receptor antagonist Ebastine was used to observe the clinical efficacy of umbilical therapy in treatment of chronic urticaria with blood-deficiency and wind-dryness,and explore the feasibility and safety of this therapy.Methods:Patients with chronic urticaria who met the criteria were randomly divided into blank-controlled group,treatment group 1,and treatment group 2.The basic treatment was traditional Chinese medicine decoction Danggui yinzi and Ebastine.Medicines were applied into umbilical therapy.Record the patient's symptoms at the treatment beginning,3 weeks and 6 weeks after the treatment,observe the effect level differences and symptom score drop index of each group;One month after our treatment,patients who recovered in each group were followed up to observe the recurrence rate.Results:There were 7 cases of termination or shedding,1 for blank-controlled group,4 for treatment group 1,and 2 for treatment group 2.A total of 107 cases were included in the experiment(37cases,34 cases,and 36 cases respectively).The gender,age,course of disease,severity of disease,and symptom balance before treatment in the three groups were well balanced(P>0.05),and there was no statistical difference.There was a statistically significant difference in the effect level for 3 weeks of treatment(P<0.05);The results of comparison between the two groups showed that the difference between the control group and the treatment group 1 was statistically significant(P<0.05);there was no significant difference between the control group and the treatment group 2(P>0.05);Compared treatment group lwith the treatment group 2,there was a statistically significant difference(P<0.05).The results showed that the effect level of treatment group 1 was better than that of control group and treatment group 2 in treatment for 3 weeks.There was a statistically significant difference in the effect level for 6 weeks of treatment(P<0.05);The results of the comparison between the two groups showed that the difference between the control group and the treatment group 1 was statistically significant(P<0.05);the difference is also the same between the control group and the treatment group 2(P<0.05);There was no statistical difference between the two treatment groups(P>0.05).The results showed that the efficacy of treatmentOf treatment groups was better than that of the control group after 6 weeks of treatment,and there was no statistical difference between them.There was no statistical difference in the scores of the three groups before treatment.There was a statistically significant difference in the scores between the groups treated for 3 weeks(P<0.05).It is the same as this in 6th Week.The LSD test was used to compare with each other.The results showed that there was a significant difference in treatment scores between the control group and the treatment group 1 at 3 weeks of treatment(P<0.05),and there was no difference between the control group and the treatment group 2(P>0.05);the difference between the two treatment groups was statistically significant(P<0.05).At 6 weeks of treatment,there was a statistically significant difference in the treatment scores between the control group and the treatment group 1(P<0.05),also like this between the control group and the treatment group 2(P<0.05).but there was no statistical difference between two treatment groups(P>0.05).Through the t-test,the results showed that the scores of the three groups were statistically different before and after treatment(P<0.05).Patients were followed up one month after treatment.The recurrence rates were 37.50%?7.14%?and 20.00%(3 cases,1 cases,and 2 cases respectively),and there was not statistically significant difference between the two groups.The incidence of adverse reactions related to application was 2.63%in the treatment group 1 and 5.26%in the treatment group 2.The difference was not statistically significant.Drug-related adverse reactions were four cases of drowsiness and drowsiness in the treatment group 1(10.54%),and the difference was statistically significant.Conclusion:At the 3rd week of treatment,group 1 was superior to control group and treatment group 2 in the grade of effect.At the 6th week of treatment,the effect level of treatment group 1 and treatment group 2 was better than that of the control group and there was no statistical difference between the two groups.There was no difference between the treatment groups in application allergy,but there were statistically significant differences in the use of drugs,indicating that the umbilical therapy combined with traditional Chinese medicine decoction has good effects on the treatment of chronic urticaria,but the safety of Chinese medicine is higher,so it is preferable to use traditional Chinese medicine to apply navel in the treatment of chronic urticaria.This result was influenced by many factors,such as the observation time,the number of cases,etc,and the specific mechanism of umbilical therapy needs to be studied in depth.More objective indicators should be provided to demonstrate the scientificity and accuracy. |
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